What are the most pertinent questions to ask a patient during a pharmacy Medication Therapy Management (MTM) session?

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Last updated: September 10, 2025View editorial policy

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Most Pertinent Questions to Ask During Pharmacy MTM Sessions

The most important questions during a Medication Therapy Management (MTM) session should focus on medication reconciliation, adherence assessment, and identifying drug-related problems to optimize patient outcomes and reduce mortality and morbidity risks.

Medication History and Reconciliation

  • Ask patients to bring all medications or a complete list to visits, including:

    • All prescription medications
    • Over-the-counter medications
    • Dietary or herbal supplements 1
    • Traditional and complementary medicines 2
  • Verify medication details:

    • "What is the name, strength, and dosing schedule for each medication?"
    • "When did you start taking each medication?" 2
    • "Have there been any recent changes to your medications?" 1
    • "Are you using multiple prescribers or pharmacies?" 2

Medication Understanding and Administration

  • Assess patient knowledge:

    • "What do you understand about why you're taking each medication?" 1
    • "How do you take your medication? (with/without food, whole/crushed, timing)" 2
    • "Do you use any tools to help remember your medications (pill caddies, calendars)?" 2
  • Administration challenges:

    • "Do you have any difficulty swallowing pills or using your medications?"
    • "Do you understand how to use your devices/inhalers/injections correctly?"
    • "Do you know how to store your medications properly?" 1

Medication Adherence

  • Direct adherence questions:

    • "Have you missed any doses in the past week?" 1
    • "What specific challenges do you face taking your medications as prescribed?" 1
    • "Do you ever skip doses intentionally? If so, why?" 2
  • Financial concerns:

    • "Are you having any difficulty affording your medications?" 2
    • "Are you aware of assistance programs that might help with medication costs?" 2

Side Effects and Concerns

  • Medication experience:

    • "Have you experienced any side effects from your medications?" 1
    • "Are there any medications that you're particularly concerned about?" 1
    • "Have you noticed any new symptoms since starting any medications?" 2
  • Efficacy assessment:

    • "Do you feel your medications are working for you?" 1
    • "Are your symptoms well-controlled with your current medications?" 1

Lifestyle and Health Behaviors

  • Daily habits:

    • "What is your typical daily routine, and how do your medications fit into it?" 1
    • "Do you use tobacco, alcohol, or recreational drugs?" 2
    • "What is your diet like? Do you follow any specific dietary patterns?" 2
  • Health monitoring:

    • "Do you monitor any health parameters at home (blood pressure, blood sugar)?" 1
    • "When was your last laboratory test for medication monitoring?" 1

Social and Environmental Factors

  • Support system:

    • "Who helps you manage your medications, if anyone?" 2
    • "Do you have reliable transportation to pick up your medications?" 1
    • "Where do you store your medications at home?" 2
  • Living situation:

    • "Have there been any recent changes in your living situation that affect how you take your medications?" 2
    • "Do you have any concerns about medication safety in your home?" 2

Special Population Considerations

For Older Adults

  • "Do you have any difficulty opening medication containers?" 2
  • "Have you experienced any falls recently?" 2
  • "Do you have any memory concerns that affect taking your medications?" 2

For Patients with Multiple Chronic Conditions

  • "Which health condition concerns you the most?" 1
  • "What matters most to you regarding your health and treatment?" 1

Common Pitfalls to Avoid

  1. Failing to verify all current medications - Always use at least two patient identifiers (name, date of birth) when reviewing medications 2

  2. Missing potential drug interactions - Actively review drug interactions at each encounter by asking about all medications including OTC and supplements 2

  3. Not addressing adherence barriers - Explore specific reasons for non-adherence rather than just asking if patients take their medications 1

  4. Overlooking patient priorities - Ask what matters most to patients regarding their health and treatment 1

  5. Using medical jargon - Use plain language when discussing medications and health conditions to ensure patient understanding 3

By systematically addressing these key areas during MTM sessions, pharmacists can effectively identify and resolve medication-related problems, improve adherence, and ultimately enhance patient outcomes.

References

Guideline

Medication Therapy Management (MTM) Approach

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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