Differential Diagnosis for BOOP (Bronchiolitis Obliterans with Organizing Pneumonia)
When suspecting BOOP, consider the following differential diagnoses:
- Single most likely diagnosis
- Idiopathic BOOP: This is the most common form of BOOP, and it should be suspected when there is a history of progressive cough, dyspnea, and radiographic findings of patchy infiltrates without a clear infectious or environmental cause.
- Other Likely diagnoses
- Infectious pneumonia: Bacterial, viral, or fungal infections can cause similar symptoms and radiographic findings, and should be considered, especially in immunocompromised patients.
- Chronic eosinophilic pneumonia: This condition can present with similar symptoms and radiographic findings, and is often associated with eosinophilia.
- Cryptogenic organizing pneumonia (COP): COP is a type of idiopathic interstitial pneumonia that can present with similar symptoms and radiographic findings.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Lung cancer: Although less likely, lung cancer can present with similar symptoms and radiographic findings, and is a critical diagnosis to consider, especially in patients with a history of smoking.
- Sarcoidosis: This condition can cause similar symptoms and radiographic findings, and is often associated with other systemic symptoms.
- Wegener's granulomatosis: This is a rare but potentially life-threatening condition that can cause similar symptoms and radiographic findings.
- Rare diagnoses
- Lymphomatoid granulomatosis: This is a rare condition that can cause similar symptoms and radiographic findings, and is often associated with immunocompromised states.
- Langerhans cell histiocytosis: This is a rare condition that can cause similar symptoms and radiographic findings, and is often associated with smoking and other environmental exposures.
- Alveolar proteinosis: This is a rare condition that can cause similar symptoms and radiographic findings, and is often associated with immunocompromised states.