What is the proper technique for using an inhaler spacer with a metered-dose inhaler (MDI)?

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Proper Inhaler Spacer Technique

The proper technique for using an inhaler spacer with a metered-dose inhaler (MDI) requires a slow, deep inhalation followed by a 10-second breath hold after actuation to maximize medication delivery to the lungs. 1

Correct Spacer Technique

Preparation Steps

  • Shake the MDI vigorously before use 1
  • Remove the cap from the MDI and spacer
  • Insert the MDI mouthpiece into the spacer device
  • Ensure proper assembly of the spacer 2

Inhalation Technique

  1. For adults and children ≥4 years old:

    • Place the spacer mouthpiece between teeth and seal lips around it
    • Actuate the MDI only once into the spacer 1
    • Take a slow, deep breath (30 L/min or 3-5 seconds) immediately after actuation 1
    • Hold breath for 10 seconds 1
    • If another dose is needed, wait 30-60 seconds before repeating
  2. For children <4 years old:

    • Use a spacer with a face mask attachment
    • Ensure the face mask has a tight fit 1
    • Allow 3-5 inhalations per actuation 1
    • Note: Face masks reduce delivery to lungs by approximately 50% 1

Maintenance of Spacer Devices

  • Rinse plastic spacers/valved holding chambers (VHCs) once a month with a low concentration of liquid household dishwashing detergent (1:5000 or a few drops per cup of water) 1
  • Allow to air dry completely 1
  • Do not wipe dry as this may increase static charge 3
  • Replace spacers according to manufacturer recommendations

Benefits of Using Spacers

Spacers provide several important advantages over using an MDI alone:

  • Minimize coordination difficulties between actuation and inhalation 3
  • Reduce oropharyngeal deposition of medication 1, 3
  • Increase lung deposition of medication 3
  • Decrease risk of topical side effects (e.g., thrush) with inhaled corticosteroids 1
  • Provide clinical effectiveness equal to nebulizer machines 1

Common Errors to Avoid

  • Not shaking the MDI before use 2
  • Insufficient breath holding after inhalation 2
  • Actuating multiple times into the spacer before inhaling 1
  • Exhaling into the device before inhalation 4
  • Using a spacer with accumulated static charge 3
  • Improper assembly of the spacer device 2

Special Considerations

  • If a commercial spacer is unavailable, improvised spacers made from a 500-mL plastic bottle or 150-mL disposable paper cup can provide similar drug delivery 1
  • Antistatic VHCs or properly rinsed plastic non-antistatic VHCs enhance delivery to lungs 1
  • Spacers are particularly beneficial for patients who have difficulty with proper MDI technique, including elderly patients and young children 1

By following these steps, patients can maximize the effectiveness of their inhaled medications while minimizing side effects and medication waste.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Spacer devices for metered dose inhalers.

Clinical pharmacokinetics, 2004

Guideline

Asthma Management in Patients with Exercise-Induced Bronchospasms

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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