What are Erythema Multiforme Oral lesions (EMOs)?

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Last updated: March 14, 2025 • View editorial policy

From the Guidelines

Erythema Multiforme Oral lesions (EMOs) are characterized by oral mucosal changes, including red and cracked lips, strawberry tongue, or diffuse erythema with no focal lesions, ulcerations, or exudates, as seen in Kawasaki disease 1. The clinical features of EMOs are part of the diagnostic criteria for Kawasaki disease, which is an acute, febrile, mucocutaneous condition accompanied by lymphoid involvement with specific desquamative skin lesions 1. Some key characteristics of EMOs include:

  • Red and cracked lips
  • Strawberry tongue
  • Diffuse erythema with no focal lesions, ulcerations, or exudates These oral mucosal changes can be accompanied by other symptoms such as swelling or erythema of the hands and feet, rash, and cervical lymphadenopathy 1. It is essential to note that EMOs are not the only manifestation of Kawasaki disease, and a comprehensive diagnosis should consider all the clinical features and laboratory results 1. The treatment for Kawasaki disease, which includes EMOs, typically involves intravenous immunoglobulin (IVIG) and high-dose aspirin 1.

From the Research

Definition and Characteristics of Erythema Multiforme Oral Lesions (EMOs)

There are no research papers provided to assist in answering this question about Erythema Multiforme Oral lesions (EMOs). The studies available 2, 3, 4, 5, 6 focus on opioid-associated out-of-hospital cardiac arrest, resuscitation efforts, and the administration of naloxone or epinephrine during cardiopulmonary resuscitation, which are not directly relevant to EMOs.

Relevant Information

  • The provided studies do not mention Erythema Multiforme Oral lesions (EMOs) or any related conditions.
  • The studies primarily discuss cardiopulmonary resuscitation, opioid overdose, and the use of naloxone or epinephrine in emergency medical situations 2, 3, 4, 5, 6.
  • There is no information available in the provided studies to define or describe the characteristics of EMOs.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.