Postoperative Pain Management for Patients on Chronic Opioids
For patients already on chronic opioid therapy, postoperative pain management should continue the same opioids they were taking preoperatively, while adding short-acting opioids as needed for breakthrough pain. 1
Preoperative Assessment and Planning
Evaluation of Current Opioid Regimen
- Calculate the oral morphine equivalent (OME) of the patient's current regimen
- Identify specific opioids and formulations the patient is taking
- Assess for opioid tolerance (likely at OME doses of 60 mg/day for 7 days or more) 1
Perioperative Management Plan
- Continue baseline opioids: Patients on chronic opioid therapy should continue their usual opioids throughout the surgical admission 1
- Create individualized plan: For patients on specific medications like buprenorphine or methadone, develop a tailored perioperative plan 1
- Consult specialists: For patients on high opioid doses, obtain pain specialist consultation before surgery 1
Intraoperative Considerations
- Implement multimodal analgesia techniques (regional anesthesia, NSAIDs, acetaminophen) to minimize additional opioid requirements 1
- Anticipate higher opioid requirements for adequate analgesia in opioid-tolerant patients 1
- For patients on buprenorphine specifically, evidence suggests continuing it perioperatively is appropriate 2
Postoperative Pain Management
Immediate Postoperative Period
- Continue the patient's baseline opioid regimen to prevent withdrawal 1
- Add short-acting opioids for breakthrough pain, recognizing that higher doses may be required 1
- For patients unable to take oral medications, convert to parenteral equivalents (preferably morphine) 1
Specific Recommendations for Buprenorphine
- For patients on buprenorphine, continuing their usual dose is recommended rather than discontinuing it 1, 2
- Research shows patients who received their usual buprenorphine dose postoperatively required significantly less additional opioid analgesia compared to those who did not receive their dose 2
Multimodal Approach
- Utilize non-opioid analgesics (acetaminophen, NSAIDs if not contraindicated)
- Consider adjuvant medications (gabapentinoids, ketamine) when appropriate
- Implement regional anesthesia techniques when feasible 1
Discharge Planning
- Continue the patient's baseline chronic opioid regimen 1
- Provide short-acting opioids for breakthrough pain only if needed, typically for 5-7 days maximum 1
- Clearly document in the discharge letter:
- The patient's baseline opioid regimen
- Any additional opioids prescribed for acute pain
- Duration of additional opioid therapy (typically 5-7 days) 1
- Coordinate with the patient's pain management provider for ongoing care 1
Monitoring and Follow-up
- Involve the inpatient pain service in the care of opioid-tolerant patients 1
- Arrange follow-up with the patient's pain management provider
- Consider referral to transitional pain services for complex cases 3
- Monitor for signs of inadequate pain control or adverse effects
Common Pitfalls to Avoid
- Discontinuing baseline opioids: This can lead to withdrawal and worsened pain control 1
- Underdosing: Opioid-tolerant patients often require higher doses of opioids for adequate analgesia 1
- Overreliance on opioids: Failing to implement multimodal analgesia can lead to excessive opioid use 1
- Poor coordination: Lack of communication between surgical team and pain management provider can lead to suboptimal care 1
- Inappropriate discharge planning: Failing to provide clear instructions on opioid management after discharge 1
By continuing the patient's baseline opioid regimen and adding appropriate short-acting opioids for breakthrough pain, while implementing multimodal analgesia techniques, optimal postoperative pain control can be achieved while minimizing complications related to opioid therapy.