Common Ophthalmic Emergencies and Their Immediate Treatments
Prompt recognition and immediate treatment of ophthalmic emergencies is essential to prevent permanent vision loss and should be initiated before urgent ophthalmology referral. 1
Key Ophthalmic Emergencies
1. Acute Angle-Closure Glaucoma
- Presentation: Sudden onset of unilateral painful red eye, blurry vision, constitutional symptoms 2
- Diagnosis: Confirmed by elevated intraocular pressure (IOP) measurement
- Immediate Treatment:
- Administer acetazolamide 500mg IV as initial dose followed by 125-250mg every four hours 3
- Timolol 0.5% eye drops (contraindicated in patients with asthma, bradycardia, heart block, or cardiac failure) 4
- Brimonidine eye drops (caution: may cause drowsiness, dry mouth, ocular hyperemia) 5
- Urgent ophthalmology referral for definitive treatment
2. Retinal Detachment
- Presentation: Sudden onset of floaters, flashes of light, followed by curtain-like shadow in visual field 2
- Diagnosis: Indirect ophthalmoscopy is preferred
- Immediate Treatment:
- Bed rest with affected eye positioned upward
- Eye shield protection
- Urgent ophthalmology referral for surgical repair
- No eye drops or medications are indicated initially
3. Chemical Eye Injuries
- Presentation: Pain, redness, blurred vision after chemical exposure
- Immediate Treatment:
- Immediate copious irrigation with saline or water for at least 30 minutes
- pH testing of conjunctival fornices
- Continue irrigation until pH normalizes (7.0-7.4)
- Urgent ophthalmology referral
4. Globe Rupture/Penetrating Eye Injury
- Presentation: History of trauma, decreased vision, irregular pupil, shallow anterior chamber
- Immediate Treatment:
- Do NOT apply pressure to the eye
- Rigid eye shield placement (no eye patches)
- No eye drops or ointments
- NPO status
- Antiemetics to prevent increased IOP from vomiting
- Systemic antibiotics
- Urgent ophthalmology referral 2
5. Central Retinal Artery Occlusion
- Presentation: Sudden, painless, profound vision loss
- Immediate Treatment:
- Digital ocular massage
- Anterior chamber paracentesis (by ophthalmologist)
- Acetazolamide 500mg IV 3
- Urgent ophthalmology referral
- Consider thrombolytic therapy within 4.5 hours of onset
6. Endophthalmitis
- Presentation: Severe eye pain, decreased vision, hypopyon, following eye surgery or trauma
- Immediate Treatment:
- Urgent ophthalmology referral for intravitreal antibiotics
- Systemic antibiotics may be started
7. Orbital Cellulitis
- Presentation: Eyelid swelling, proptosis, limited extraocular movements, fever
- Immediate Treatment:
- IV broad-spectrum antibiotics
- CT scan of orbits
- Urgent ophthalmology and ENT referral
8. Corneal Foreign Body/Abrasion
- Presentation: Foreign body sensation, pain, tearing, photophobia
- Immediate Treatment:
- Foreign body removal (if visible and superficial)
- Antibiotic eye drops
- Cycloplegic eye drops for comfort
- Eye patching is generally not recommended
- Ophthalmology follow-up within 24 hours
Important Considerations
Time-Critical Nature: Delay in treatment can result in permanent vision loss, especially in conditions like central retinal artery occlusion (4-6 hour window) and acute angle-closure glaucoma 1
Medication Cautions:
Examination Pearls:
- Visual acuity assessment is the vital sign of the eye
- Pupillary reactions help identify optic nerve involvement
- Slit lamp examination is essential for anterior segment evaluation
- Tonometry for IOP measurement in suspected glaucoma
- Fundoscopic examination to assess retina and optic nerve
Common Pitfalls:
- Failing to recognize time-sensitive emergencies
- Removing protruding foreign bodies from penetrating eye injuries
- Delaying referral for conditions requiring immediate surgical intervention
- Using topical anesthetics for pain control (can delay healing and mask worsening symptoms)
Ophthalmic emergencies account for approximately 3% of emergency department visits, and while rarely life-threatening, they can lead to significant morbidity including permanent vision loss if not promptly addressed 6.