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Last updated: September 11, 2025View editorial policy

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Differential Diagnosis for Scarring to Anterior Stomach

Single Most Likely Diagnosis

  • Peptic ulcer disease: This is the most common cause of scarring in the stomach, particularly in the anterior wall, due to the high prevalence of Helicobacter pylori infection and the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Other Likely Diagnoses

  • Gastric cancer: Although less common than peptic ulcer disease, gastric cancer can cause scarring, especially if it has been treated with surgery, radiation, or chemotherapy.
  • Chronic gastritis: Inflammation of the stomach lining can lead to scarring, particularly in the anterior stomach, due to various causes such as H. pylori infection, autoimmune disorders, or chronic use of NSAIDs.

Do Not Miss Diagnoses

  • Gastric lymphoma: A type of cancer that can cause scarring in the stomach, and if missed, can lead to severe consequences, including intestinal obstruction, bleeding, or perforation.
  • Scleroderma: A rare autoimmune disorder that can cause fibrosis and scarring in the stomach, leading to gastric dysfunction and potentially life-threatening complications.

Rare Diagnoses

  • Crohn's disease: A type of inflammatory bowel disease that can affect the stomach and cause scarring, although it is more commonly associated with the small intestine and colon.
  • Eosinophilic gastritis: A rare condition characterized by inflammation of the stomach lining due to an eosinophilic infiltration, which can lead to scarring and gastric dysfunction.
  • Gastric tuberculosis: A rare infection that can cause scarring and inflammation in the stomach, often associated with pulmonary tuberculosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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