Pediatric Dosing of Dextromethorphan Syrup
Dextromethorphan (Pedicloryl) syrup should be dosed at 0.25 mg/kg every 4 hours for children 2-5 years old, not exceeding 600 mg in 24 hours.
Age-Based Dosing Recommendations
The dosing of dextromethorphan (Pedicloryl) syrup varies based on the child's age:
- Children 2-5 years old: 50-100 mg every 4 hours, not to exceed 600 mg in 24 hours 1
- Children 6-11 years old: Dosing should be based on clinical trials showing efficacy in this age group with standard pediatric dosing 2
Administration Guidelines
When administering dextromethorphan syrup to pediatric patients, follow these important guidelines:
- Use a calibrated medication syringe or cup for accurate measurement 1
- Avoid using household spoons as they can deliver inconsistent volumes (flatware tablespoons can range from 7-14 ml) 3
- Liquid/syrup formulations are preferred for young children for ease of administration 1
- Limit treatment duration to 7 days unless otherwise directed by a healthcare provider 1
Safety Considerations
Several safety considerations should be kept in mind when prescribing dextromethorphan:
- Monitor for common side effects including nausea, vomiting, stomach pain, or dizziness 1
- Ensure adequate hydration during treatment to help with mucus thinning 1
- Discontinue use and consult a healthcare provider if symptoms worsen or persist beyond 7 days 1
- Be aware that pediatric patients require individualized dosing based on age, size, and organ maturity—not simply reduced adult doses 4
Common Errors to Avoid
- Using adult formulations or "eyeballing" doses without proper measurement tools 1
- Using combination products that may lead to overdosing of certain components 1
- Extended use beyond recommended duration without medical supervision 1
- Inadequate hydration during treatment 1
When to Seek Medical Attention
Contact a healthcare provider immediately if:
- The child develops a high fever
- Cough persists for more than 7 days
- Symptoms worsen despite treatment
- Any unusual or severe side effects occur 1
Remember that pediatric dosing requires special consideration of developmental physiology and pharmacokinetic parameters that differ from adults 5. Accurate dosing is critical to ensure both efficacy and safety in this vulnerable population.