Primary Treatment for Failure to Thrive in Toddlers
The primary treatment for a toddler with failure to thrive (FTT) is nutritional rehabilitation with a high-energy and high-protein diet, targeting 150 kcal and 3g protein per kg body weight daily, divided into 4-6 meals per day. 1
Diagnostic Criteria
- Weight below the 10th percentile for age
- Weight crossing two or more major percentile lines downward
- Weight-for-height below the 10th percentile
- Severe malnutrition: weight below 70% of expected weight-for-height (Z-score < -3)
Assessment Process
Growth parameter evaluation:
- Plot weight, length, and head circumference on appropriate growth charts
- Calculate weight-for-length ratio
- Determine rate of weight gain/loss
Nutritional assessment:
- Detailed dietary history (24-hour recall, 3-5 day diet record)
- Feeding behaviors and patterns
- Caregiver-child interactions during feeding
Medical evaluation:
- Physical examination for signs of underlying medical conditions
- Assess hydration status
- Check for signs of systemic illness
Treatment Algorithm
Step 1: Calculate Energy Requirements
- Use Schofield's equation to determine resting energy expenditure (REE)
- Add factors for physical activity and catch-up growth
- Alternative: Double the REE for catch-up growth
- Target weight gain: 17-20 grams/kg/day 1
Step 2: Implement Nutritional Interventions
For breastfed infants:
- Increase feeding frequency
- Consider fortifying expressed breast milk
For formula-fed infants:
- Use high-energy/protein infant formula
- Increase caloric density (up to 30 kcal/oz)
For toddlers on solid foods:
- Increase meal frequency (4-6 meals/day)
- Fortify foods with extra fats/oils
- Provide calorie-dense foods
- Add nutritional supplements as needed
Step 3: Monitor Progress
- Weekly weight checks initially
- Adjust nutritional plan based on response
- Target energy requirements by age:
- Infants (0-1 year): 75-85 kcal/kg/day
- Toddlers (1-7 years): 65-75 kcal/kg/day 1
Indications for Referral
- Severe malnutrition (Z-score < -3) with medical instability: immediate referral to emergency room
- Failure to respond to outpatient nutritional management
- Suspected underlying medical condition requiring specialist evaluation
- Concerns about neglect or psychosocial issues
Multidisciplinary Approach
A team-based approach is essential and should include:
- Primary care physician
- Nutritionist/dietitian
- Feeding specialist (occupational therapist)
- Social worker (if psychosocial issues identified)
- Subspecialists as needed (gastroenterologist, endocrinologist) 2
Common Pitfalls to Avoid
- Overlooking psychosocial factors: Most cases of FTT involve inadequate caloric intake due to behavioral or psychosocial issues 2
- Excessive laboratory testing: Routine laboratory testing rarely identifies a cause and is not generally recommended 2
- Delayed intervention: Early detection and intervention minimize long-term disadvantages in growth, behavior, and development
- Neglecting follow-up: Children discharged from acute care should be scheduled for follow-up within 24-48 hours 1
- Refeeding syndrome: In severely malnourished children, increase food intake gradually and monitor electrolytes (phosphate, magnesium, potassium) 1
Early identification and appropriate nutritional management are critical for preventing long-term consequences of FTT, including impaired cognitive development and immune function 3.