Ankle Sprain Treatment Protocol
The appropriate treatment for an ankle sprain should follow the PRICE protocol (Protection, Rest, Ice, Compression, Elevation) initially, followed by early functional treatment with semi-rigid or lace-up supports and a progressive rehabilitation program including proprioceptive and strengthening exercises. 1
Initial Management (First 48-72 Hours)
PRICE Protocol:
- Protection: Avoid activities that cause pain
- Rest: Limit weight-bearing as needed
- Ice: Apply cold therapy for 20-30 minutes, 3-4 times daily
- Compression: Consider compression wrap for comfort (not primarily for swelling reduction)
- Elevation: Keep the ankle elevated to reduce swelling
Pain Management:
- NSAIDs (e.g., naproxen, celecoxib) to reduce pain and inflammation
- Diclofenac shows superior results compared to ibuprofen for pain during motion 1
- Alternative: Acetaminophen 1000mg every 6 hours (max 4000mg daily) 1
- Topical diclofenac gel can provide localized pain relief with fewer systemic side effects 1
Support and Weight-Bearing:
Functional Rehabilitation (Begin within 48-72 hours)
Early Mobilization:
Progressive Exercise Program:
Advanced Rehabilitation:
Imaging Considerations
Use Ottawa Ankle Rules to determine if radiographs are necessary (sensitivity 96%, specificity 98%) 1:
- Inability to bear weight immediately after injury
- Point tenderness over the malleoli, talus, or calcaneus
If symptoms persist despite normal radiographs, consider MRI to evaluate:
- Ligament integrity
- Cartilage damage
- Synovitis or impingement lesions
- Osteochondral lesions not visible on radiographs 1
Prevention of Recurrence
- Use semi-rigid ankle support for sports activities for at least 6 weeks 1
- Implement long-term proprioceptive training (reduces relative risk of recurrence by 38%) 1
- Continue strengthening exercises even after return to full activity 1
Common Pitfalls to Avoid
- Overreliance on elastic bandages: Semi-rigid or lace-up supports are more effective 1
- Prolonged immobilization: This delays recovery compared to early functional treatment 1
- Inadequate rehabilitation: Comprehensive rehabilitation is essential to prevent recurrence 2
- Discontinuing crutches too early: Continue until walking without significant pain or limping 1
- Neglecting proprioceptive training: Critical for preventing recurrent sprains 1
Special Considerations
- For persistent symptoms despite conservative treatment for 4-6 months, consider surgical options including anatomic repair and reconstructions 1
- Arthroscopic intervention may be considered for refractory cases or professional athletes requiring rapid recovery 1
- Manual therapy combined with supervised exercise may lead to better recovery than home exercises alone 3