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Last updated: September 12, 2025View editorial policy

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Differential Diagnosis

  • Single most likely diagnosis
    • Migraine: The patient has a history of migraines, and her symptoms of headaches, nausea/vomiting, and body aches are consistent with a migraine episode. The fact that darkness helps alleviate her symptoms also supports this diagnosis, as many migraine sufferers find relief in a quiet, dark environment.
  • Other Likely diagnoses
    • Viral illness (e.g., influenza, viral gastroenteritis): The patient's symptoms of headaches, body aches, and nausea/vomiting could be indicative of a viral illness. The lack of response to Tylenol and the presence of body aches suggest that this could be a possible diagnosis.
    • Tension headache: Although the patient has a history of migraines, her symptoms could also be consistent with a tension headache, especially if she is experiencing stress or anxiety.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Subarachnoid hemorrhage: Although unlikely, a sudden and severe headache (often described as "the worst headache of my life") could be indicative of a subarachnoid hemorrhage, which is a life-threatening condition that requires immediate medical attention.
    • Meningitis: The patient's symptoms of headaches, nausea/vomiting, and body aches could be indicative of meningitis, especially if she is experiencing fever, stiff neck, or photophobia.
    • Temporal arteritis: This condition can cause headaches, nausea/vomiting, and body aches, especially in older adults. If left untreated, temporal arteritis can lead to blindness and other serious complications.
  • Rare diagnoses
    • Cluster headache: Although rare, cluster headaches can cause severe, one-sided headaches that are accompanied by nausea/vomiting and body aches.
    • Trigeminal neuralgia: This condition can cause sudden, severe facial pain that may be accompanied by headaches and nausea/vomiting.
    • Idiopathic intracranial hypertension: This condition can cause headaches, nausea/vomiting, and body aches, especially in young, obese women.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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