Primary Biliary Cholangitis (PBC): This condition is characterized by chronic inflammation and scarring of the bile ducts within the liver, leading to cholestasis. Itching (pruritus) is a common symptom, often without specific skin findings, and elevated liver enzymes are typical. The daily consumption of wine could contribute to liver enzyme elevation but is not the primary cause of PBC. PBC is more common in women, especially in this age group.

Alcoholic Liver Disease: Given the patient's daily wine consumption, alcoholic liver disease is a consideration. Itching can be a symptom due to bile duct obstruction or liver dysfunction, and elevated liver enzymes are consistent with this diagnosis.
Non-Alcoholic Fatty Liver Disease (NAFLD): Although less directly linked to itching, NAFLD can cause elevated liver enzymes. Itching might be less common but can occur, especially if there's associated liver dysfunction or other metabolic syndrome components.
Drug-Induced Liver Injury: Certain medications can cause liver enzyme elevations and itching. A thorough medication history is necessary to consider this diagnosis.

Cholestasis due to Pancreatic Cancer: Although less common, pancreatic cancer can cause obstructive jaundice and itching due to bile duct obstruction. It's crucial to consider this diagnosis, especially in an older adult, due to its severe implications.
Hemochromatosis: A genetic disorder leading to iron overload, which can cause liver enzyme elevation and potentially itching. It's essential to diagnose due to the availability of treatment and the potential for severe complications if left untreated.
Wilson's Disease: A rare genetic disorder causing copper accumulation in the liver, leading to liver damage. It can present with liver enzyme elevation and neurological symptoms but is less likely given the patient's age and presentation.

Sjögren's Syndrome: An autoimmune disorder that can affect exocrine glands, including the liver, leading to cholestasis and itching. It's less common and typically associated with other systemic symptoms like dry eyes and mouth.
Sarcoidosis: A condition characterized by the formation of granulomas in various organs, including the liver, which can cause liver enzyme elevation and itching. It's rare and usually presents with other systemic symptoms.