Differential Diagnosis for Thickness of Tendons in Hand
Single Most Likely Diagnosis
- Dupuytren's Contracture: A condition characterized by the thickening of the palmar fascia, leading to nodules and cord formation in the hand, which can cause the tendons to appear thickened. It's a common condition, especially in older adults, and has a strong genetic predisposition.
Other Likely Diagnoses
- Rheumatoid Arthritis (RA): An autoimmune disorder that can cause inflammation and thickening of the tendons in the hand, among other symptoms. RA is a common condition that affects the joints and surrounding tissues.
- Tendinosis/Tendinitis: Conditions caused by inflammation or degeneration of the tendons, which can lead to thickening. These conditions are common in individuals who perform repetitive activities or have experienced trauma to the hand.
- Ganglion Cysts: Non-cancerous lumps that can develop on the tendons or joints of the hand, causing them to appear thickened. These cysts are common and usually benign.
Do Not Miss Diagnoses
- Infectious Tenosynovitis: A serious infection of the tendon sheath, which can cause rapid swelling and thickening of the tendons. If left untreated, it can lead to severe complications, including tendon rupture and permanent damage.
- Gout: A form of arthritis caused by the buildup of uric acid crystals in the joints, which can lead to sudden and severe inflammation of the tendons. If not treated promptly, gout can cause permanent joint damage.
Rare Diagnoses
- Amyloidosis: A condition characterized by the deposition of abnormal proteins (amyloid) in various tissues, including the tendons, which can cause thickening. Amyloidosis is a rare condition that can be associated with other systemic diseases.
- Scleroderma: A chronic autoimmune disorder that can cause thickening and hardening of the skin and connective tissues, including the tendons. Scleroderma is a rare condition that can lead to significant disability if not treated properly.
- Ehlers-Danlos Syndrome: A group of genetic disorders that affect the body's connective tissue, including the tendons, which can cause hypermobility and thickening. Ehlers-Danlos Syndrome is a rare condition that requires careful management to prevent complications.