Management of Bee Sting Injuries: Tetanus and Antibiotic Considerations
Tetanus prophylaxis is not routinely needed after a simple bee sting unless your tetanus vaccination is not current (within 10 years for clean minor wounds or 5 years for contaminated wounds). 1, 2
Tetanus Prophylaxis Decision-Making
Bee stings are generally considered clean, minor wounds unless they become contaminated or infected. The need for tetanus prophylaxis depends on your vaccination history:
If you have completed primary tetanus vaccination series:
If you have not completed primary vaccination or vaccination status is unknown:
- Tetanus toxoid (Td/Tdap) should be administered regardless of wound type
- Tetanus Immune Globulin (TIG) may also be needed for contaminated wounds 3
Antibiotic Therapy for Bee Stings
Routine antibiotic prophylaxis is not indicated for uncomplicated bee stings. 1
Antibiotics should only be considered in specific circumstances:
- Signs of infection: Increasing redness, warmth, swelling, pain, or purulent drainage
- High-risk patients: Immunocompromised individuals, those with asplenia, advanced liver disease
- High-risk wounds: Moderate to severe injuries, especially to the hand or face 1
If infection develops (which is rare with bee stings), consider antibiotics that cover skin flora:
- Amoxicillin-clavulanate: 875/125 mg twice daily
- Cephalexin: 250-500 mg four times daily
- Clindamycin: 300-400 mg three times daily (for penicillin-allergic patients) 1
Proper Bee Sting Management
Remove the stinger immediately (if present) - the method is less important than speed of removal 1
Clean the wound thoroughly with soap and water 1
Manage local symptoms:
- Apply cold compresses to reduce pain and swelling
- Consider oral antihistamines for itching
- Use acetaminophen or NSAIDs for pain relief 1
Monitor for allergic reactions:
When to Seek Medical Attention
- Signs of infection: increasing redness, warmth, swelling, pain, or drainage
- Signs of systemic allergic reaction: hives, swelling away from sting site, difficulty breathing, dizziness
- Stings in or near the eye, mouth, or throat 1, 4
Important Caveats
- Bee sting allergies can be life-threatening - systemic reactions require immediate medical attention 1, 4
- Rare but serious infections can occur after bee stings, including endophthalmitis if the sting is near the eye 5
- Patients with a history of systemic reactions to insect stings should carry autoinjectable epinephrine and consider referral to an allergist 1
In summary, most uncomplicated bee stings do not require tetanus prophylaxis (unless your vaccination is not current) or antibiotics (unless signs of infection develop). Focus on proper wound care, symptom management, and monitoring for allergic reactions.