Heart Failure: This is the most likely diagnosis given the combination of bilateral pedal edema and ventricular ectopic beats on ECG. Heart failure can lead to fluid buildup in the body, causing edema, and ventricular ectopics can be a sign of underlying cardiac dysfunction.

Hypertension: Uncontrolled hypertension can lead to heart failure and also cause edema due to fluid retention. The presence of ventricular ectopics could be indicative of hypertensive heart disease.
Renal Disease: Conditions like nephrotic syndrome or chronic kidney disease can cause significant edema due to protein loss and fluid retention, respectively. Ventricular ectopics might be seen in the context of electrolyte imbalances associated with renal disease.
Thyroid Disease: Both hypothyroidism and hyperthyroidism can cause edema, though the mechanisms differ. Hypothyroidism can lead to fluid retention, while hyperthyroidism can cause increased cardiac output leading to heart failure symptoms, including edema. Ventricular ectopics can occur due to the metabolic effects of thyroid hormones on the heart.

Pulmonary Embolism: Although less common, pulmonary embolism can cause sudden onset of edema, especially if it leads to right heart strain. Ventricular ectopics could be seen in the context of acute right heart dysfunction. This diagnosis is critical to not miss due to its high mortality rate if untreated.
Cardiac Tamponade: This condition, characterized by fluid accumulation in the pericardial sac, can compress the heart and lead to edema due to decreased cardiac output. Ventricular ectopics might be seen due to the mechanical stress on the heart. It's a medical emergency that requires prompt diagnosis and treatment.
Acute Coronary Syndrome: Myocardial infarction or acute coronary syndrome can cause heart failure leading to edema and ventricular ectopics. It's crucial to consider this diagnosis, especially in a patient with risk factors for coronary artery disease.

Constrictive Pericarditis: A condition where the pericardium becomes stiff and fibrotic, constricting the heart and potentially leading to edema due to impaired cardiac filling. Ventricular ectopics could be seen due to the abnormal mechanical forces on the heart.
Lymphatic Obstruction: Conditions that obstruct lymphatic drainage, such as lymphoma or filariasis, can cause localized or generalized edema. However, the presence of ventricular ectopics on ECG would be less directly related to this condition, making it a less likely but still possible diagnosis in the right clinical context.