What is the first step when a patient complains of a headache?

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First Step in Headache Evaluation

The first step when a patient complains of headache is to perform a thorough history taking and physical examination to distinguish between primary and secondary headaches, and to identify red flags that may indicate a more serious underlying condition. 1

Initial Assessment: Focus on Red Flags

When evaluating a patient with headache, prioritize identifying these red flags that warrant urgent attention:

  • "Worst headache of life"
  • New headache pattern after age 50
  • Headache worsened by Valsalva maneuver
  • Headache that awakens patient from sleep
  • Headache with focal neurological deficits
  • Recent head or neck injury
  • Abrupt onset headache
  • Headache associated with exertion or sexual activity
  • Systemic signs/symptoms (fever, weight loss)
  • Secondary risk factors (cancer, HIV) 1, 2

Key Components of History Taking

  1. Headache characteristics:

    • Location (unilateral vs. bilateral)
    • Quality (pulsating, throbbing, pressure)
    • Intensity (mild, moderate, severe)
    • Duration (hours, days)
    • Frequency (episodic vs. chronic)
    • Aggravating/alleviating factors
    • Associated symptoms (nausea, vomiting, photophobia, phonophobia)
  2. Timing and pattern:

    • New vs. recurrent headache
    • Acute vs. gradual onset
    • Progression pattern
    • Relationship to activities or time of day

Focused Neurological Examination

The American Academy of Neurology recommends a complete neuro-ophthalmologic examination including:

  • Visual acuity testing
  • Visual field testing
  • Fundoscopic examination
  • Extraocular movement assessment
  • Pupillary responses 1

Additionally, perform:

  • Mental status assessment
  • Cranial nerve examination
  • Motor and sensory testing
  • Deep tendon reflexes
  • Coordination testing
  • Meningeal signs

Decision Algorithm After Initial Assessment

Based on the American Academy of Family Physicians recommendations:

  1. If red flags present:

    • Urgent neuroimaging (MRI with contrast preferred over CT for non-emergent situations)
    • Consider referral to emergency department or neurology
  2. If no red flags and pattern suggests primary headache:

    • Classify according to International Headache Society criteria
    • Initiate appropriate treatment based on headache type and severity

Common Pitfalls to Avoid

  • Failure to identify secondary headaches
  • Overlooking medication overuse headache
  • Misdiagnosis of migraine
  • Inadequate treatment leading to chronic daily headache 1

Remember that while most headaches are benign primary headache disorders, missing a serious secondary cause can lead to significant morbidity and mortality. The history and physical examination are the most critical tools in making this distinction.

References

Guideline

Headache Diagnosis and Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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