What are the possible causes and management for an 87-year-old man with resolved SVT, history of AF, on Apixaban (apixaban), with CKD and elevated Troponin levels?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 87-year-old Man with Resolved SVT and Troponin Elevation

Single Most Likely Diagnosis

  • Myocardial Infarction (MI): The rise in troponin levels from 0.08 to 0.5, although not extremely high, in the context of a recent episode of SVT and left shoulder pain, suggests myocardial injury. The patient's age and history of AF increase the risk for coronary artery disease and MI.

Other Likely Diagnoses

  • Myopericarditis: The left shoulder pain during the SVT episode could be referred pain from the pericardium, and the troponin elevation could be due to myocardial inflammation rather than infarction.
  • Cardiac Strain from SVT: Prolonged or rapid SVT can cause cardiac strain, leading to troponin elevation without an acute coronary syndrome.
  • Chronic Kidney Disease (CKD) related troponin elevation: CKD can cause chronic troponin elevation due to decreased renal clearance, but the acute rise in this case suggests an acute cardiac event.

Do Not Miss Diagnoses

  • Aortic Dissection: Although less likely, the left shoulder pain and troponin elevation could be indicative of an aortic dissection, which is a medical emergency. The patient's age and history of hypertension (possibly contributing to CKD) increase the risk.
  • Pulmonary Embolism (PE): The left shoulder pain could be referred pain from a PE, and the troponin elevation could be due to right ventricular strain. The patient's history of AF increases the risk for PE.
  • Apixaban-related bleeding: Although apixaban is an anticoagulant, it can cause bleeding, and the troponin elevation could be due to cardiac tamponade or other bleeding complications.

Rare Diagnoses

  • Takotsubo Cardiomyopathy: The left shoulder pain and troponin elevation could be due to stress-induced cardiomyopathy, although this is less likely in the context of SVT and AF.
  • Coronary Artery Spasm: The troponin elevation could be due to coronary artery spasm, which is a rare cause of cardiac chest pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.