What is the cause of a painful plantar wart (plantar wart refers to a wart on the sole of the foot) on the bottom of my foot?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a Painful Lesion on the Bottom of the Foot

  • Single Most Likely Diagnosis
    • Plantar wart: This is the most likely diagnosis due to the description of the lesion and its location on the bottom of the foot. Plantar warts are common and can be painful, especially when pressure is applied to them while walking.
  • Other Likely Diagnoses
    • Corn or callus: These are areas of thickened skin that can develop in response to repeated pressure or friction, which could cause pain when walking.
    • Plantar keratosis: A thickening of the skin on the bottom of the foot that can be painful, especially if it becomes inflamed.
    • Ingrown toenail: Although typically found on the toes, an ingrown toenail can cause pain on the bottom of the foot if it becomes infected or inflamed.
  • Do Not Miss Diagnoses
    • Plantar melanoma: A type of skin cancer that can present as a new or changing lesion on the bottom of the foot. It's crucial to not miss this diagnosis due to its potential for serious consequences if left untreated.
    • Deep tissue infection (e.g., plantar abscess): An infection that can cause significant pain and swelling, and if not properly treated, can lead to more severe complications.
    • Foreign body (e.g., a splinter or glass shard): An object embedded in the foot can cause pain and potentially lead to infection if not removed.
  • Rare Diagnoses
    • Plantar fibroma: A rare, benign tumor of the foot that can cause pain and discomfort.
    • Neuroma: A growth or tumor of nerve tissue that can cause pain, numbness, or tingling, typically between the toes but potentially on the bottom of the foot.
    • Erythromelalgia: A rare disorder characterized by burning pain, heat, and redness in the hands and feet, which could potentially cause pain on the bottom of the foot.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.