Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Severe Right Lower Abdominal Pain

Single Most Likely Diagnosis

  • Appendicitis: The sudden onset of severe right lower abdominal pain, tenderness, rebound tenderness, and guarding are classic signs of appendicitis. The patient's age and presentation are also consistent with this diagnosis.

Other Likely Diagnoses

  • Ovarian Torsion: The severe pain and sudden onset could be indicative of ovarian torsion, especially given the patient's gender. This condition requires prompt surgical intervention.
  • Ectopic Pregnancy: Although less likely if the patient is not known to be pregnant, ectopic pregnancy can present with severe abdominal pain and should be considered, especially if there's a possibility of pregnancy.
  • Ruptured Ovarian Cyst: A ruptured ovarian cyst can cause severe pain and may lead to hemodynamic instability, fitting the patient's presentation.

Do Not Miss Diagnoses

  • Ruptured Ectopic Pregnancy: This is a life-threatening condition that requires immediate diagnosis and treatment. Even if the patient denies pregnancy, it should be considered due to the severity of symptoms.
  • Intestinal Obstruction: Although less common in young adults without prior abdominal surgery, intestinal obstruction can cause severe abdominal pain, vomiting, and signs of peritonitis.
  • Mesenteric Ischemia: This condition can present with severe abdominal pain out of proportion to physical findings and can lead to bowel infarction if not promptly treated.

Rare Diagnoses

  • Endometriosis: While endometriosis can cause chronic pelvic pain, it is less likely to cause acute, severe pain leading to syncope.
  • Inflammatory Bowel Disease (IBD) Flare: Although IBD can cause severe abdominal pain, it typically has a more chronic course and is less likely to present with such an acute onset.
  • Primary Peritonitis: This condition is rare in immunocompetent individuals but can occur, especially in females, and presents with diffuse or localized abdominal pain and signs of peritonitis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.