Recommended Application Amount for 1% Diclofenac Gel
For 1% diclofenac gel (Voltaren), apply 2 pump actuations (40 mg) to each affected area, twice daily. 1
Application Instructions
The FDA-approved dosing for topical diclofenac is specific and should be followed carefully:
- Apply to clean, dry skin
- Dispense 40 mg (2 pump actuations) directly onto the affected area or first into the hand and then onto the affected area
- Spread evenly around the treatment area
- Wash hands completely after application
- Wait until the area is completely dry before covering with clothing or applying other topical products 1
Important Considerations
Timing and Duration
- Avoid showering/bathing for at least 30 minutes after application
- Wait until the treated area is completely dry before applying sunscreen, insect repellant, lotion, or other topical medications 1
- For pain management, diclofenac sodium 1% gel is typically applied twice daily 1
Safety Precautions
- Avoid skin-to-skin contact between other people and the treated area until completely dry
- Do not get the gel in your eyes, nose, or mouth
- Do not apply to open wounds
- Avoid external heat and occlusive dressings on treated areas 1
Systemic Exposure
- Topical diclofenac 1% gel has 5-17 fold lower systemic exposure compared to oral diclofenac, making it a safer alternative for patients at risk for NSAID-related adverse effects 2
- The limited systemic absorption results in fewer gastrointestinal side effects compared to oral NSAIDs 2
Clinical Efficacy
When used as directed, topical diclofenac demonstrates good efficacy:
- For pain management, proper application provides effective relief with minimal systemic effects 2
- For treatment of actinic keratosis (when using the 3% formulation), twice daily application for 60-90 days is recommended 3
Common Pitfalls to Avoid
- Using too little product (less than 2 pump actuations per application)
- Applying to wet or recently washed skin, which can affect absorption
- Not allowing adequate drying time before covering the area
- Combining with oral NSAIDs without medical supervision, which increases risk of adverse effects 1
Remember that the vehicle and formulation characteristics are important determinants of absorption, so follow the specific application instructions for the 1% formulation rather than applying instructions for other concentrations.