What is the treatment for a wasp sting?

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Last updated: September 14, 2025View editorial policy

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Wasp Sting Treatment

For wasp stings, immediate treatment includes removing the stinger (if present), washing with soap and water, applying ice or cold compresses, and using over-the-counter pain relievers and antihistamines for symptom management. 1

Initial Management

  1. Immediate wound care:

    • Remove the stinger immediately if present (wasps can typically sting multiple times without losing their stinger, unlike bees) 1, 2
    • Clean the area thoroughly with soap and water 1
    • Apply cold compresses or ice packs with a thin barrier between ice and skin to reduce pain and swelling 1
  2. Symptom management:

    • Take oral antihistamines to reduce itching and swelling 1
    • Use acetaminophen or NSAIDs for pain relief 1
    • Apply topical treatments such as lidocaine or corticosteroid lotions for local symptom relief 2

Monitoring for Allergic Reactions

Watch for signs of allergic reactions, which can range from mild to severe:

  • Local reactions: Redness, swelling, and pain at the sting site 1, 2
  • Regional reactions: More extensive swelling beyond the sting site 2
  • Systemic reactions (anaphylaxis): Require immediate medical attention 1
    • Signs include: flushing, syncope, tachycardia, hypotension, convulsions, vomiting, diarrhea, abdominal cramps, airway swelling, laryngospasm, bronchospasm, pruritus, urticaria, and angioedema 3

Emergency Treatment for Anaphylaxis

If signs of anaphylaxis develop:

  • Administer intramuscular epinephrine immediately - this is the first-line treatment 1, 3
    • Adult dose: 0.3-0.5 mg
    • Children dose: 0.01 mg/kg up to 0.3 mg
  • Seek emergency medical attention immediately 1
  • Patients with known allergies should carry autoinjectable epinephrine 1

Special Considerations

  1. Tetanus prophylaxis:

    • Not routinely needed after simple insect stings unless tetanus vaccination is not current 1
    • Consider a tetanus booster if it's been more than 5 years since the last dose for contaminated wounds 1
  2. Antibiotic prophylaxis:

    • Not indicated for uncomplicated stings 1
    • May be considered if signs of infection develop or in high-risk patients (immunocompromised, asplenic, advanced liver disease) 1
  3. Alternative treatment options:

    • Concentrated heat application has shown promise in reducing swelling, pain, and itching quickly after insect stings 4

Prevention of Future Stings

  • Have known nests removed by professionals 1
  • Avoid wearing bright colors or flowery prints 1
  • Wear protective clothing (long pants, long sleeves, closed shoes) 1
  • Individuals with history of systemic reactions should be referred to an allergist-immunologist for consideration of venom immunotherapy 1, 5

Common Pitfalls and Caveats

  • Never delay epinephrine administration in cases of anaphylaxis to try other medications first 1
  • The onset of life-threatening anaphylactic signs typically occurs within 10 minutes of the sting, requiring prompt recognition and treatment 2
  • Anaphylactic reactions are not dose-dependent or related to the number of stings 2
  • Patients with mastocytosis are at higher risk for severe reactions to insect stings 5
  • Venom immunotherapy significantly reduces the risk of subsequent systemic reactions from as high as 60% to as low as 5% 1, 5

References

Guideline

Insect Sting Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Hymenoptera stings.

Clinical techniques in small animal practice, 2006

Research

Insect stings: clinical features and management.

Deutsches Arzteblatt international, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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