Best Interventions for Cervical Spondylosis
For cervical spondylotic myelopathy (CSM), surgical decompression is strongly recommended for patients with moderate to severe myelopathy (mJOA ≤12), while mild myelopathy (mJOA >12) can be treated with either surgical decompression or short-term nonoperative therapy for up to 3 years. 1
Assessment and Classification
The management of cervical spondylosis depends on the clinical presentation:
- Cervical Spondylotic Myelopathy (CSM) - spinal cord compression
- Cervical Radiculopathy - nerve root compression
- Axial Neck Pain - without neurological symptoms
Key Diagnostic Indicators
- MRI cervical spine without contrast is the preferred imaging modality 1
- Consider CT myelography if MRI is contraindicated
- Red flags requiring immediate surgical referral: gait instability, decreased hand dexterity, hyperreflexia, Hoffmann's sign, Babinski sign, bladder/bowel dysfunction 1
Treatment Algorithm
1. Cervical Spondylotic Myelopathy (CSM)
Moderate to Severe CSM (mJOA ≤12):
- First-line: Surgical decompression 2, 1
- Benefits maintained for 5-15 years postoperatively
- Earlier intervention associated with better outcomes
- Anterior approach preferred for 1-3 level disease
- Posterior approach may be better for ≥4 level disease 2
Mild CSM (mJOA >12):
- Option 1: Surgical decompression
- Option 2: Nonoperative therapy (for up to 3 years) 2, 1
- Cervical collar immobilization
- Activity modification
- Anti-inflammatory medications
- Close monitoring for neurological deterioration
2. Cervical Radiculopathy
First-line: Conservative management 2, 3
- NSAIDs and other analgesics
- Physical therapy with neck muscle strengthening exercises
- Cervical traction 4
- Activity modification and posture correction
Second-line: Surgical intervention (if persistent symptoms or progressive neurological deficit) 2
- Posterior cervical laminoforaminotomy - 90-97% good to excellent results 2
- Anterior cervical discectomy and fusion (ACDF)
3. Axial Neck Pain without Neurological Symptoms
- First-line: Conservative management 5, 3
- NSAIDs and muscle relaxants
- Physical therapy with isometric exercises
- Cervical collar (short-term use)
- Activity modification
Prognostic Factors
Poor outcomes are associated with:
- Age over 75 years 1
- Longer duration of symptoms before treatment 1
- More severe preoperative neurological dysfunction 1
- Presence of abnormal EMG findings 1
- Cervical instability 1
Surgical Considerations
Anterior vs. Posterior Approach
Anterior approach (ACDF or corpectomy):
Posterior approach (laminectomy with/without fusion, laminoplasty):
Complications to Consider
- Pseudarthrosis (nonunion) after fusion associated with poorer outcomes 2
- Late deterioration more common with laminectomy alone (29%) 2
- Adjacent segment degeneration after fusion 2
Important Caveats
Avoid spinal manipulation with high-velocity thrusts in patients with cervical spondylosis, especially those with spinal fusion or advanced spinal osteoporosis 2
Prolonged nonoperative management in moderate to severe myelopathy can lead to irreversible spinal cord damage 1
Surgical outcomes decline with long-term follow-up, raising questions about the natural course of the disease 5
Total hip arthroplasty is strongly recommended for patients with cervical spondylosis and advanced hip arthritis 2
Elective spinal osteotomy is conditionally recommended against in patients with severe kyphosis 2
By following this evidence-based approach, clinicians can optimize outcomes for patients with cervical spondylosis while minimizing complications and disability.