From the Research
For nasal congestion, use your medications in this order: saline rinse first, followed by Avamys (fluticasone furoate nasal spray), and then Drixoral (pseudoephedrine/dexbrompheniramine) last. Start with the saline rinse to clean your nasal passages, which helps remove mucus and allergens while improving the effectiveness of the medications that follow, as supported by a study on saline nasal irrigations for chronic rhinosinusitis 1. Wait about 5-10 minutes after the rinse before using Avamys, a corticosteroid that reduces inflammation, which has been shown to be effective in relieving nasal symptoms of perennial allergic rhinitis when used once daily 2. Avamys works best when used consistently every day, preferably in the morning. Take Drixoral at least 30 minutes after Avamys, as it contains a decongestant and antihistamine that provide more immediate relief. Drixoral is typically taken twice daily, but avoid taking it late in the evening as it may cause insomnia. These medications can be used together safely, but Drixoral should only be used short-term (3-5 days) to avoid rebound congestion, while Avamys and saline rinses can be used long-term, as rebound congestion is a concern with prolonged use of decongestants 3. A recent study on the efficacy and safety of Fluticasone Furoate and Oxymetazoline Nasal Spray also supports the use of fluticasone furoate for managing allergic rhinitis with nasal congestion, without causing rebound congestion when used continuously for 28 days 4. If your congestion persists beyond 7-10 days, consult a healthcare provider.
Some key points to consider:
- The order of medication use is important to maximize effectiveness and minimize side effects.
- Saline rinses can be used long-term and are a useful adjunct to other treatments.
- Avamys (fluticasone furoate) is a effective treatment for allergic rhinitis and can be used once daily.
- Drixoral (pseudoephedrine/dexbrompheniramine) should be used short-term to avoid rebound congestion.
- Consult a healthcare provider if congestion persists beyond 7-10 days.
The most recent and highest quality study 4 supports the use of fluticasone furoate for managing allergic rhinitis with nasal congestion, and provides guidance on the safe use of decongestants to avoid rebound congestion.