Tymlos (Abaloparatide) Pen Requirements for Monthly Dosing
For a patient prescribed Tymlos (abaloparatide) at the standard dose of 80 mcg daily, one pen is needed per month.
Medication Information and Dispensing Details
Tymlos is supplied as a pre-assembled single-patient-use disposable pen that contains:
- 3120 mcg of abaloparatide in 1.56 mL (2000 mcg/mL) solution 1
- Each pen delivers 30 daily doses of 80 mcg abaloparatide in 40 mcL 1
- One pen provides exactly a 30-day supply when used at the recommended dose
Administration and Storage Guidelines
Administration
- Tymlos is administered as a subcutaneous injection once daily
- The standard therapeutic dose is 80 mcg daily 1, 2
- Each pen is designed to deliver precisely 30 doses at this concentration
Storage Requirements
- Before first use: Store under refrigeration between 2°C to 8°C (36°F to 46°F) 1
- After first use: Store for up to 30 days at 20°C to 25°C (68°F to 77°F) 1
- Do not freeze or subject to heat
- Discard the pen after 30 days, even if it still contains unused solution 1
Important Clinical Considerations
Prescription Planning
- For a 30-day prescription, dispense one pen
- For a 90-day prescription, dispense three pens
- Sterile needles are not included with the pen and must be prescribed separately 1
Patient Education Points
- Each pen should be used for only one patient
- Patients should not share pens or needles with others
- The pen should be discarded after 30 days of use, even if solution remains 1
- Patients should be instructed on proper sharps disposal
Potential Pitfalls to Avoid
- Underprescribing: Prescribing less than one pen per month will result in missed doses
- Storage errors: Improper storage can affect medication stability
- Needle confusion: Remember that needles are not included with the pen and must be prescribed separately
- Pen sharing: Emphasize that pens are for single-patient use only to prevent infection risk
The clear dosing schedule of one pen per 30 days simplifies prescription planning and ensures patients receive the full therapeutic benefit of Tymlos for osteoporosis management.