Recommended Dosage of Aspercreme (Trolamine Salicylate)
The recommended dosage of Aspercreme (trolamine salicylate) is to apply the cream topically to the affected area 3-4 times daily.
Product Information
Aspercreme contains trolamine salicylate, which is a salicylate derivative used for topical pain relief. Unlike salicylic acid (which is used for acne treatment), trolamine salicylate is specifically formulated for musculoskeletal pain relief.
Application Instructions
- Apply Aspercreme to clean, dry skin
- Use enough cream to cover the painful area completely
- Massage gently until absorbed
- Repeat application 3-4 times daily or as needed for pain relief
- Wash hands after application unless treating hands
Mechanism and Absorption
Trolamine salicylate works differently from other topical salicylates like methyl salicylate. Research shows that trolamine salicylate:
- Has significant local tissue penetration into underlying muscles 1
- Produces much lower systemic absorption compared to methyl salicylate 2
- Concentrates in muscle tissue beneath the application site at levels up to 49 times higher than in untreated muscle areas 1
Efficacy
Clinical research supports the effectiveness of trolamine salicylate for muscular soreness:
- A double-blind study showed that 10% trolamine salicylate cream reduced both duration and severity of exercise-induced muscle soreness 3
- It has also demonstrated effectiveness in combination with other agents for improving tissue perfusion in compromised skin flaps 4
Safety Considerations
- Avoid applying to broken or irritated skin
- Do not bandage tightly or apply heat to the treated area
- Do not use with other topical products on the same area unless directed by a healthcare provider
- Discontinue use if excessive skin irritation develops
- Unlike methyl salicylate, trolamine salicylate has minimal systemic absorption, making it a safer option for patients who need to avoid systemic salicylates 2
Special Populations
- Pregnancy: Use with caution (Category C)
- Nursing mothers: Avoid applying to chest area if breastfeeding
- Children: Use caution in children under 12 years of age
Important Warnings
- Do not use with heating pads or other heat sources
- Do not ingest
- Avoid contact with eyes
- Discontinue use and consult a healthcare provider if pain persists for more than 7 days or worsens
- Consult a healthcare provider before use if you have salicylate sensitivity or are taking blood thinners
Remember that Aspercreme (trolamine salicylate) is for external use only and should not be applied to open wounds or damaged skin.