From the Guidelines
To address low Vascular Endothelial Growth Factor (VEGF) associated with mold toxicity, the most critical step is to remove oneself from the mold-contaminated environment and remediate the living space professionally, as emphasized by the guidelines from the US Environmental Protection Agency (EPA) and the CDC 1.
Key Considerations
- Eliminating mold exposure is crucial, and individuals can usually clean up mold-contaminated areas less than 10 ft2, but professional help is recommended for larger areas or when the heating, ventilating, and air conditioning (HVAC) system is involved 1.
- For detoxification, consider using binders like activated charcoal (1-2 capsules twice daily between meals) or prescription cholestyramine (4g twice daily) to help eliminate mycotoxins, as these can support the body's natural detoxification processes.
- Supporting liver function with supplements like milk thistle (150mg twice daily) and glutathione (250-500mg daily) is also essential, as a healthy liver is critical for overall detoxification and health.
Boosting VEGF Levels
- Incorporating moderate exercise for 30 minutes daily can naturally increase VEGF levels, as physical activity is known to enhance VEGF production.
- Consider supplements that support VEGF production, including resveratrol (100-200mg daily), curcumin (500-1000mg daily with black pepper extract), and omega-3 fatty acids (1-2g daily), as these have been shown to promote VEGF production and overall health.
- Ensuring adequate vitamin D levels (2000-5000 IU daily) and zinc (15-30mg daily) is also vital, as deficiencies in these nutrients can impair VEGF function and overall health.
Additional Therapies
- Hyperbaric oxygen therapy sessions may also help increase VEGF production, as this therapy can enhance blood vessel formation and tissue repair.
- It is essential to note that while these interventions can support VEGF production and overall health, the primary focus should always be on eliminating the root cause of the problem, which in this case is mold exposure.
From the Research
Treatment Options for Low VEGF Levels in Mold Toxicity
There are no direct research papers that discuss treatment options for low Vascular Endothelial Growth Factor (VEGF) levels in the context of mold toxicity.
Related Research on Mold Toxicity
- Studies have investigated the relationship between mold exposure and various health conditions, including respiratory problems and non-respiratory conditions 2, 3.
- Some research suggests that mold exposure can cause allergies, asthma, and hypersensitivity pneumonitis, but the concept of "toxic mold syndrome" has been disputed 4, 5.
- The role of mycotoxins in mold toxicity is also a topic of debate, with some studies finding no evidence to support their involvement in disease causation 4.
VEGF and Cardiovascular Toxicity
- Research has explored the relationship between VEGF and cardiovascular toxicity, particularly in the context of anti-VEGF/VEGFR agents used in cancer therapy 6.
- Cardiovascular toxicity is a significant risk associated with these agents, and guidelines are being developed for prevention, monitoring, and treatment 6.
Limitations
- There is a lack of research specifically addressing low VEGF levels in the context of mold toxicity, making it difficult to provide evidence-based treatment options.