Dehydration: This is a common cause of elevated globulin levels due to hemoconcentration. Even mild dehydration can cause a relative increase in globulin levels because the concentration of globulins increases as the volume of plasma decreases.

Infections: Chronic or acute infections can cause an increase in globulin levels as part of the body's immune response. This includes bacterial, viral, or parasitic infections.
Inflammatory Conditions: Conditions like rheumatoid arthritis, lupus, or other autoimmune diseases can lead to elevated globulin levels due to chronic inflammation.
Hepatic Conditions: Certain liver diseases, such as hepatitis or cirrhosis, can cause an increase in globulin production.

Multiple Myeloma: Although rare in children, multiple myeloma is a plasma cell disorder that can cause a significant increase in globulin levels. It's crucial to rule out this condition due to its severe implications.
Lymphoma: Both Hodgkin's and non-Hodgkin's lymphoma can present with elevated globulin levels. Early detection is critical for effective treatment.
Chronic Hepatitis B or C: These infections can lead to liver cirrhosis and hepatocellular carcinoma if not treated. Elevated globulin levels can be an indicator of chronic infection.

Waldenström's Macroglobulinemia: A rare type of non-Hodgkin's lymphoma characterized by an overproduction of IgM, leading to elevated globulin levels.
Alpha-1 Antitrypsin Deficiency: A genetic disorder that can cause liver disease and elevated globulin levels due to the accumulation of abnormal proteins.
Hypergammaglobulinemia: A condition characterized by an excessive production of gamma globulins, which can be primary (idiopathic) or secondary to other conditions.