What is the treatment for Stroke (STREAT)?

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Last updated: March 15, 2025View editorial policy

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From the Guidelines

The treatment for acute ischemic stroke due to large-vessel occlusion should be intravenous alteplase and endovascular therapy (mechanical clot removal), with a combined endovascular therapy approach using stent-retrievers and aspiration being the most effective way to achieve fast first-pass complete reperfusion 1. The goal of treatment is to rapidly restore blood flow to the affected area of the brain, and the most recent evidence suggests that a combined approach is the most effective way to achieve this 1.

Key Considerations

  • Time is of the essence in treating acute ischemic stroke, and rapid patient transfer, diagnosis, and treatment are crucial 1.
  • The use of intravenous alteplase and endovascular therapy has been shown to be highly effective in improving outcomes for patients with acute ischemic stroke due to large-vessel occlusion 1.
  • A combined endovascular therapy approach using stent-retrievers and aspiration is the most effective way to achieve fast first-pass complete reperfusion, and should be used whenever possible 1.

Treatment Options

  • Intravenous alteplase: this is a highly effective treatment for acute ischemic stroke, and should be administered as soon as possible after onset of symptoms 1.
  • Endovascular therapy: this involves the use of mechanical devices to remove the clot and restore blood flow to the affected area of the brain, and has been shown to be highly effective in improving outcomes for patients with acute ischemic stroke due to large-vessel occlusion 1.

Important Considerations

  • The organization of existing systems of care, and particularly pre-hospital transfer systems, have to be changed to diagnose and treat patients as fast as possible 1.
  • Several different transport models are currently in use, and the optimal patient transfer paradigm is highly dependent on local geography and hospital efficiency 1.

From the Research

Treatment for Stroke

There are no research papers to assist in answering this question, as the provided studies do not discuss the treatment for stroke. The studies focus on various topics such as:

  • Cognitive intervention research 2
  • Self-management, self-care, and self-help in adolescents with emotional problems 3
  • Autism spectrum disorder 4
  • Brain fog and neuroinflammation 5
  • Anxiety disorders 6 These studies do not provide information on the treatment for stroke, and therefore, it is not possible to provide a comprehensive answer to this question based on the available evidence.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Autism spectrum disorder.

Nature reviews. Disease primers, 2020

Research

Brain Fog: A Bit of Clarity Regarding Etiology, Prognosis, and Treatment.

Journal of psychosocial nursing and mental health services, 2021

Research

Anxiety disorders.

Lancet (London, England), 2021

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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