Management of Substernal Chest Pain
If you experience substernal chest pain, you should immediately call 911 (emergency services) for urgent transport to the nearest emergency department, as this could indicate a life-threatening condition requiring immediate medical attention. 1, 2
Initial Assessment and Triage
Substernal chest pain requires immediate evaluation as it may represent acute coronary syndrome (ACS) or other life-threatening conditions. The approach should follow this algorithm:
- Call emergency services (911) - Do not drive yourself to the hospital or delay seeking care 1
- Emergency medical services will:
- Perform an ECG within 10 minutes of arrival
- Transport you urgently to the emergency department
- Begin appropriate initial treatment (oxygen if needed, aspirin, IV access)
Potential Causes of Substernal Chest Pain
Substernal chest pain can indicate several serious conditions:
- Acute Coronary Syndrome - Characterized by pressure, heaviness, tightness, or squeezing in the chest that may radiate to arms, jaw, or back 1
- Aortic Dissection - Sudden onset of severe, ripping pain, often described as "worst pain of life" 1
- Pulmonary Embolism - Associated with dyspnea, tachycardia, and pain that worsens with inspiration 1
- Esophageal Rupture - Associated with vomiting, subcutaneous emphysema 1
- Pericarditis - Pain that worsens when lying flat and improves when leaning forward 1, 2
- Pneumothorax - Sudden onset of sharp pain with dyspnea 1
Warning Signs Requiring Immediate Medical Attention
Seek emergency care immediately if your substernal chest pain is accompanied by:
- Shortness of breath
- Diaphoresis (sweating)
- Nausea or vomiting
- Radiation of pain to jaw, neck, arms, or back
- Dizziness or lightheadedness
- Pain occurring with exertion or emotional stress
- Pain in someone with risk factors for heart disease (hypertension, diabetes, smoking, high cholesterol)
What to Expect in the Emergency Department
The emergency department will perform:
- Immediate ECG - To look for signs of heart attack or ischemia 1
- Cardiac biomarker testing (troponin) - To check for heart damage 1
- Physical examination - To help identify the cause of chest pain 1
- Additional testing based on initial findings:
- Chest X-ray
- Additional ECGs
- Cardiac stress testing
- CT scan or other imaging if non-cardiac causes are suspected
Common Pitfalls to Avoid
- Delaying medical care - "Wait and see" approaches can be dangerous with substernal chest pain 2
- Self-diagnosing as "just indigestion" - Cardiac pain can mimic gastrointestinal symptoms 2
- Assuming pain must be severe to be serious - Even mild chest discomfort can indicate a serious condition 1
- Relying on nitroglycerin response to diagnose - Relief with nitroglycerin is not diagnostic of cardiac pain 1, 2
Key Point
The American Heart Association and American College of Cardiology guidelines emphasize that the initial evaluation of substernal chest pain should focus on rapidly identifying life-threatening causes 1. Time is critical - minutes lost can result in permanent heart damage or death. When in doubt, seek emergency medical care immediately.