Is thyroglobulin (TG) elevated in subacute thyroiditis?

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From the Research

Thyroglobulin (TG) Levels in Subacute Thyroiditis

  • Thyroglobulin (TG) levels are elevated in subacute thyroiditis, as reported in several studies 1, 2, 3, 4.
  • A study published in the Archives of Internal Medicine found that serum TG levels were elevated in 92% of patients with subacute "painful" thyroiditis in the early stage 4.
  • Another study published in the European Journal of Endocrinology found that immunoreactive TG from subacute thyroiditis (ST) sera sedimented in a single, rather symmetrical peak as purified 19S TG 1.
  • Elevated TG levels are a characteristic feature of subacute thyroiditis, and serial measurements of serum TG can help in diagnosing and monitoring the disease 4.
  • The elevation of TG levels in subacute thyroiditis is thought to be due to the release of TG from damaged thyroid tissue into the circulation 1, 4.

References

2
Research

Graves' disease occurring after subacute thyroiditis: report of a case and review of the literature.

Thyroid : official journal of the American Thyroid Association, 1996

3
Research

Thyroiditis: differential diagnosis and management.

American family physician, 2000

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