What is the cause of decreased libido in a man with normal testosterone levels, who consumes wine (2 times per week), smokes (occasionally), and uses marijuana (2 times a day)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 15, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Loss of Libido

  • Single Most Likely Diagnosis
    • Chronic Marijuana Use: The patient's daily use of marijuana is a significant contributor to his loss of libido. Marijuana's active ingredient, THC, can affect hormone levels and neurotransmitters that regulate sexual function, leading to decreased libido.
  • Other Likely Diagnoses
    • Alcohol Use: Although the patient only drinks wine 2 times a week, chronic alcohol use can still impact libido by affecting hormone levels, particularly testosterone, and altering brain chemistry.
    • Smoking: Occasional smoking can also contribute to decreased libido due to its negative effects on cardiovascular health and hormone regulation.
    • Psychological Factors: Stress, anxiety, or depression, which are not mentioned but could be underlying issues, often contribute to loss of libido.
  • Do Not Miss Diagnoses
    • Hypogonadism: Despite the patient's normal testosterone levels, it's essential to consider hypogonadism, as it can cause loss of libido. Further evaluation might be necessary to rule out this condition.
    • Pituitary or Testicular Disorders: Disorders affecting the pituitary gland or testes can lead to hormonal imbalances that cause loss of libido.
    • Medication Side Effects: Certain medications, not mentioned in the scenario, can significantly impact libido. It's crucial to inquire about any prescription or over-the-counter medications the patient might be taking.
  • Rare Diagnoses
    • Hyperprolactinemia: A condition characterized by elevated prolactin levels, which can suppress testosterone production and lead to loss of libido.
    • Chronic Illness: Certain chronic illnesses, such as diabetes, can cause loss of libido due to their effects on blood flow, nerve damage, and hormonal changes.
    • Sleep Apnea: Untreated sleep apnea can lead to decreased libido due to the lack of quality sleep and potential hormonal imbalances.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.