What is the best treatment for a severely symptomatic posterior anal fissure?

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Last updated: February 10, 2025View editorial policy

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From the Guidelines

The best treatment for a severely symptomatic posterior anal fissure is lateral internal sphincterotomy after 8 weeks of non-operative management.

Treatment Approach

  • Non-operative management should be attempted for 6-8 weeks, including dietary and lifestyle modifications, and medical therapy, before considering surgical treatment 1.
  • If non-operative management fails, lateral internal sphincterotomy is the preferred surgical technique due to its high healing rate of over 90%, lower recurrence rate, and higher patient satisfaction 1.
  • Both open and closed lateral internal sphincterotomy have similar results, but open lateral internal sphincterotomy may be associated with higher post-operative pain and delayed wound healing at 1 year 1.

Key Considerations

  • Surgical treatment is not recommended for acute anal fissures, but rather for chronic cases that are non-responsive to non-operative management 1.
  • Fissurectomy and posterior sphincterotomy are not preferred techniques due to lower healing rates, higher post-operative pain, and increased risk of fecal incontinence compared to lateral internal sphincterotomy 1.

From the Research

Treatment Options for Severely Symptomatic Posterior Anal Fissure

  • Medical treatment is non-specific, aimed at softening the stool and facilitating regular bowel movements, resulting in healing of almost 50% of acute anal fissures 2
  • Specific medical treatment can be offered to reversibly decrease hypertonic sphincter spasm if non-specific medical treatment fails 2
  • Surgery remains the most effective long-term treatment and should be offered for cases of chronic or complicated anal fissure, as well as for acute anal fissure with severe pain or for recurrent fissure despite optimal medical treatment 2, 3

Surgical Treatment

  • Lateral internal sphincterotomy (LIS) is the best-evaluated technique and remains the gold standard in English-speaking countries 2, 4, 5
  • Fissurectomy with posterior midline sphincterotomy and anoplasty (FPSA) is a surgical technique that has been successfully used to treat chronic anal fissures 6
  • Other techniques, such as calibrated sphincterotomy and sphincteroplasty, have been described to reduce the risk of incontinence 2

Considerations for Treatment

  • The risk of recurrent fissure remains high if the causative factors persist 2
  • The choice of treatment should take into account the patient's willingness to accept the potential risk of fecal incontinence 3, 4
  • Non-surgical therapies, such as topical sphincter relaxants or botulin toxin injection, may be considered as a first-line treatment for patients with severe, unrelenting pain and no incontinence risk factors 3, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Update on the management of anal fissure.

Journal of visceral surgery, 2015

Research

Systematic review: the treatment of anal fissure.

Alimentary pharmacology & therapeutics, 2006

Research

Identifying the best therapy for chronic anal fissure.

World journal of gastrointestinal pharmacology and therapeutics, 2011

Research

Anal Fissure - an extensive update.

Polski przeglad chirurgiczny, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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