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Last updated: September 16, 2025View editorial policy

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Differential Diagnosis for Vomiting

  • Single most likely diagnosis:
    • Gastroenteritis: This is often the most common cause of vomiting, especially in children and young adults, due to its high prevalence and the ease with which gastrointestinal viruses are transmitted.
  • Other Likely diagnoses:
    • Food poisoning: Similar to gastroenteritis, food poisoning is a common cause of vomiting, resulting from the consumption of contaminated or spoiled food.
    • Viral gastroenteritis (e.g., norovirus, rotavirus): These viruses are highly contagious and can cause severe vomiting, especially in closed environments like cruise ships, schools, and hospitals.
    • Motion sickness: A common condition that occurs in response to certain motions, such as during travel by car, boat, plane, or other vehicle.
    • Pregnancy-related morning sickness: For women of childbearing age, morning sickness is a classic symptom of early pregnancy.
  • Do Not Miss diagnoses:
    • Appendicitis: Although less common, appendicitis can present with vomiting and is a surgical emergency that requires prompt diagnosis and treatment to prevent perforation and peritonitis.
    • Intestinal obstruction: This condition, which can be caused by various factors including adhesions, hernias, or tumors, is characterized by severe vomiting and abdominal pain, and requires immediate medical attention.
    • Pancreatitis: Inflammation of the pancreas can cause severe vomiting, along with abdominal pain, and is a condition that necessitates urgent medical evaluation.
    • Meningitis: While less common, meningitis (inflammation of the protective membranes covering the brain and spinal cord) can present with vomiting, especially in children, and is a medical emergency.
  • Rare diagnoses:
    • Brain tumors: Certain brain tumors, especially those that increase intracranial pressure, can cause vomiting, often accompanied by other neurological symptoms.
    • Increased intracranial pressure (ICP): Conditions that lead to increased pressure within the skull, such as traumatic brain injury or cerebral edema, can cause vomiting.
    • Porphyrias: A group of rare genetic disorders that can cause a variety of symptoms, including severe vomiting.
    • Cyclic vomiting syndrome: A rare condition characterized by recurring episodes of severe vomiting, often without an identifiable cause.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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