Discharge Criteria for Patients with Alcohol Withdrawal Syndrome
Patients with alcohol withdrawal syndrome should only be discharged when they are clinically sober, can safely care for themselves, and have been referred to specialized addiction services for ongoing care. 1
Assessment of Readiness for Discharge
Clinical Stability Criteria
- CIWA-Ar score consistently <8 (mild withdrawal) for at least 24 hours
- No signs of delirium tremens (which typically begins 48-72 hours after last drink)
- Resolution of any withdrawal seizures (if they occurred)
- Stable vital signs
- Mental status returned to baseline
Risk Factors That May Delay Discharge
- History of withdrawal seizures or delirium tremens
- Significant medical or psychiatric comorbidities
- Failed outpatient treatment previously
- Lack of social support or unsafe discharge environment
Monitoring Timeline and Protocol
Initial 24-48 hours: Most critical period for monitoring
- Regular CIWA-Ar assessments (every 1-4 hours depending on severity)
- Monitor vital signs
- Assess for signs of worsening withdrawal
48-72 hours: Peak risk period for delirium tremens
- Continue monitoring but may decrease frequency if symptoms improving
- Ensure benzodiazepine taper is appropriate
72+ hours: Pre-discharge phase
- CIWA-Ar scores should be consistently <8
- Patient should demonstrate ability to maintain hydration and nutrition
- No signs of impending complications
Pharmacological Considerations Before Discharge
Ensure appropriate tapering of benzodiazepines to avoid withdrawal symptoms 2
- For diazepam: gradual taper to discontinue or reduce dosage to prevent withdrawal reactions
- If withdrawal reactions develop, consider pausing the taper or returning to previous dosage level
Complete thiamine supplementation (100-300 mg/day) to prevent Wernicke encephalopathy 1
Correct any electrolyte abnormalities, particularly magnesium, potassium, and phosphate 1
Discharge Planning Requirements
Addiction Services Referral
- All patients must be referred to specialized addiction services for ongoing care 1
- Consider medications to prevent relapse (acamprosate, naltrexone, disulfiram)
Follow-up Plan
- Schedule follow-up appointment within 1 week of discharge
- Provide clear instructions for medication management
Patient Education
- Signs and symptoms requiring immediate medical attention
- Importance of abstinence and continued treatment
Special Considerations
Patients with Alcoholic Liver Disease: Use benzodiazepines cautiously with monitoring due to risk of excessive sedation or precipitating hepatic encephalopathy; lorazepam and oxazepam are preferred agents 3
Outpatient Management: Only appropriate for patients with mild to moderate withdrawal symptoms without additional risk factors for developing severe or complicated withdrawal 4
Elderly Patients: May require lower doses of medications and longer monitoring periods before discharge 2
Common Pitfalls to Avoid
Premature Discharge: Discharging before the 72-hour mark when risk of delirium tremens is still present
Inadequate Follow-up Planning: Failure to establish clear continuity of care
Overlooking Comorbidities: Mental health issues or medical conditions may need stabilization before discharge
Insufficient Patient Education: Patients and caregivers must understand warning signs requiring immediate medical attention
Abrupt Discontinuation of Benzodiazepines: Can precipitate withdrawal symptoms; gradual tapering is essential 2
By following these guidelines, healthcare providers can ensure safe discharge of patients with alcohol withdrawal syndrome while minimizing the risk of complications or readmission.