Treatment of Subdural Hematoma
Surgical evacuation is the definitive treatment for acute subdural hematomas with significant mass effect, with craniotomy or craniectomy preferred over burr holes for complete evacuation of the hematoma and relief of pressure. 1
Classification and Initial Management
Subdural hematomas are classified based on timing:
- Acute subdural hematoma (ASDH): Occurs within 24 hours of trauma
- Subacute subdural hematoma: Between 24 hours and 2 weeks
- Chronic subdural hematoma (CSDH): Develops over weeks to months
Initial Assessment
- Imaging: CT scan is the first-line imaging modality
- Clinical evaluation: Glasgow Coma Scale (GCS), pupillary response, neurological deficits
- Determine need for immediate intervention
Treatment Algorithm for Acute Subdural Hematoma
Immediate Surgical Evacuation Indicated For:
- Thickness exceeding 10mm
- Midline shift greater than 5mm
- Neurological deterioration
- Signs of increased intracranial pressure
- GCS decline
Surgical Approaches:
- Craniotomy/craniectomy: Preferred for acute subdural hematomas with significant mass effect 1
- Decompressive craniectomy: May be considered for patients in coma, with large hematomas and significant midline shift, or with elevated ICP refractory to medical management 2
Medical Management:
- Mannitol: For reduction of intracranial pressure and brain mass 3
- Rapid reversal of anticoagulation: If patient is on anticoagulant therapy
- ICP monitoring: For patients with GCS ≤8
Treatment Algorithm for Chronic Subdural Hematoma
Surgical Management:
- Burr hole craniostomy with closed-system drainage: Method of choice for initial treatment, even in cases with preoperative detection of neomembranes 4
- Craniotomy: Reserved for patients with reaccumulating hematoma or residual hematoma membranes preventing brain reexpansion 4
Conservative Management May Be Considered For:
- Asymptomatic or mildly symptomatic patients
- Small hematomas (<3mm thickness) without significant mass effect
- High surgical risk patients
Pharmacological Therapy:
- Dexamethasone: May be considered in select cases, particularly for hematomas without hyperdense components, though recent trials suggest limited efficacy in symptomatic patients 5
Post-Treatment Management
Monitoring:
- Follow-up imaging: CT scan within 24 hours post-surgery
- Neurological assessment: Regular monitoring for signs of deterioration
Antiplatelet/Anticoagulation Management:
- Restart timing: Antiplatelet therapy may be safely restarted 4-8 weeks after intracranial hemorrhage in patients with strong indications 1
- Risk assessment: Balance risk of recurrent bleeding against thromboembolic risk
Predictors of Poor Outcome and Recurrence
Risk Factors for Requiring Delayed Surgery After Initial Conservative Treatment:
- Large hematoma volume
- Significant brain atrophy
- Hematoma density characteristics 6
- Presence of focal neurological deficits
- Greater midline shift
Risk Factors for Recurrence After Surgery:
- Use of antiplatelet/anticoagulant medications
- Brain atrophy
- Incomplete evacuation
- Inadequate brain re-expansion
Special Considerations
Cerebellar Subdural Hematoma:
- Lower threshold for surgical intervention due to risk of brainstem compression
- Suboccipital decompression and hematoma evacuation may improve outcomes 2
Anticoagulation-Associated Subdural Hematoma:
- Rapid reversal of anticoagulation prior to surgery
- Careful consideration of risks/benefits before restarting anticoagulation
- Generally wait 4 weeks after surgical removal or stabilization before restarting anticoagulation 1
Pitfalls to Avoid
- Delayed recognition: Maintain high index of suspicion in elderly patients with minor trauma
- Inadequate surgical decompression: Ensure complete evacuation of hematoma
- Premature restart of anticoagulation: Wait appropriate time (typically 4 weeks) after stabilization
- Missing bilateral hematomas: Always evaluate for contralateral hematoma
- Failure to identify underlying cause: Consider vascular abnormalities, coagulopathies, or other predisposing factors
The treatment approach should prioritize rapid intervention for acute subdural hematomas with significant mass effect, while chronic subdural hematomas can often be effectively managed with less invasive burr hole drainage procedures.