What is the recommended diet for Familial Mediterranean Fever (FMF)?

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Last updated: March 16, 2025View editorial policy

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From the Research

The recommended diet for Familial Mediterranean Fever (FMF) is an anti-inflammatory diet, specifically a Mediterranean-style diet rich in omega-3 fatty acids, fruits, vegetables, whole grains, and legumes, while limiting processed foods, refined sugars, and red meat, as supported by the most recent study 1. This dietary approach is based on the principle of reducing overall inflammation in the body, which can help decrease the frequency and severity of FMF attacks. The Mediterranean-style diet has been shown to have anti-inflammatory effects, and its components, such as omega-3 fatty acids, antioxidants, and fiber, may help alleviate symptoms of FMF.

Some key components of the recommended diet include:

  • Fatty fish, such as salmon and sardines, rich in omega-3 fatty acids
  • Olive oil, nuts, and seeds, which are rich in healthy fats and antioxidants
  • Fruits and vegetables, which are rich in antioxidants, fiber, and other essential nutrients
  • Whole grains, such as brown rice, quinoa, and whole-wheat bread, which are rich in fiber and nutrients
  • Legumes, such as lentils, chickpeas, and beans, which are rich in protein, fiber, and nutrients

It is also important to limit or avoid certain foods that may trigger or exacerbate FMF symptoms, such as:

  • Processed foods, which are high in unhealthy fats, salt, and sugar
  • Refined sugars, which can cause inflammation and worsen symptoms
  • Red meat, which can be high in saturated fats and pro-inflammatory compounds
  • Gluten, dairy, or nightshade vegetables (tomatoes, peppers, eggplants), which may trigger symptoms in some individuals

Staying well-hydrated is also crucial, especially during flare-ups, and careful food journaling can help identify specific triggers and personalize the diet. However, it is essential to note that dietary modifications should always complement, not replace, prescribed medications like colchicine, which remains essential for preventing amyloidosis and other serious complications of FMF, as highlighted in studies 2, 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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