How to remove a fibroid specimen after laparoscopic myomectomy?

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Last updated: September 18, 2025View editorial policy

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Specimen Removal After Laparoscopic Myomectomy

The safest and most effective method for removing fibroid specimens after laparoscopic myomectomy is in-bag contained extraction to prevent tissue dissemination, with manual morcellation preferred over power morcellation when possible. 1

Extraction Techniques

In-Bag Extraction (Preferred Method)

  • Place the enucleated fibroid into a specimen retrieval bag before extraction
  • Extract through one of the following methods:
    • Manual morcellation with scalpel or scissors within the bag
    • Contained fragmentation through minilaparotomy incision
    • Posterior colpotomy for larger specimens

Technique Selection Based on Fibroid Size

  1. Small fibroids (<3-4 cm):

    • Direct removal through slightly enlarged port site
    • Removal through posterior colpotomy
  2. Medium fibroids (4-8 cm):

    • In-bag manual morcellation
    • Contained fragmentation through minilaparotomy
  3. Large fibroids (>8 cm):

    • In-bag manual morcellation through extended umbilical incision
    • Posterior colpotomy with in-bag extraction

Risks of Uncontained Morcellation

Uncontained power morcellation has fallen out of favor due to significant risks:

  • Dissemination of occult malignancies (leiomyosarcoma risk ~1 in 2000 procedures) 2
  • Parasitic myomas from retained tissue fragments 3
  • Iatrogenic endometriosis
  • Retained tissue causing persistent pain 4

Evidence-Based Considerations

  • In-bag morcellation may take slightly longer than uncontained power morcellation (approximately 2.6 minutes longer) but provides critical safety benefits 2
  • Even exceptionally large fibroids (up to 4 kg) can be successfully removed laparoscopically using contained tissue fragmentation techniques 5
  • All tissue pieces must be diligently removed, as even small fragments can develop into parasitic fibroids if they find a blood supply 3

Technical Pearls

  • Ensure complete bag integrity throughout the extraction process
  • Maintain pneumoperitoneum during in-bag morcellation
  • Consider posterior colpotomy for large specimens when appropriate
  • Document complete removal of all tissue fragments
  • Thoroughly irrigate the abdominal cavity after specimen removal

Complications to Monitor

  • Accidental bag disruption during extraction
  • Incomplete tissue removal
  • Bleeding from extraction site
  • Infection at extraction site

By following these principles, surgeons can minimize the risks associated with specimen removal after laparoscopic myomectomy while maintaining the benefits of minimally invasive surgery, including shorter hospital stays and faster recovery compared to open procedures 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

In-bag manual versus uncontained power morcellation for laparoscopic myomectomy.

The Cochrane database of systematic reviews, 2020

Research

Parasitic myoma after morcellation.

Journal of gynecological endoscopy and surgery, 2009

Research

Retained myoma after laparoscopic supracervical hysterectomy with morcellation.

The Journal of the American Association of Gynecologic Laparoscopists, 1998

Research

Minimally invasive surgical techniques versus open myomectomy for uterine fibroids.

The Cochrane database of systematic reviews, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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