Differential Diagnosis for Symmetrical Blanchable Hand Rash
- Single most likely diagnosis
- Erythema multiforme: This condition is characterized by symmetrical, blanchable rashes often on the hands and feet, and is commonly triggered by infections or medications.
- Other Likely diagnoses
- Contact dermatitis: A common condition caused by skin contact with an allergen or irritant, leading to a blanchable rash that can be symmetrical if exposure is bilateral.
- Psoriasis: Although typically non-blanchable due to its characteristic scaling, early stages or certain types like guttate psoriasis might present with blanchable lesions and can be symmetrical.
- Dyshidrotic eczema: Characterized by small, itchy blisters on the hands and feet, which can appear symmetrical and may initially present with blanchable rashes.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN): Although these conditions typically present with non-blanchable lesions due to epidermal detachment, early stages might be blanchable. They are life-threatening and require immediate medical attention.
- Kawasaki Disease: An acute febrile illness that can present with symmetrical rash, among other criteria. It's crucial to diagnose early to prevent cardiac complications.
- Rare diagnoses
- Scleroderma: A chronic autoimmune disease that can cause skin thickening and tightening, potentially leading to symmetrical changes on the hands, though it's less likely to present as a blanchable rash.
- Systemic Lupus Erythematosus (SLE): A systemic autoimmune disease that can cause a variety of skin manifestations, including rashes that might be symmetrical and blanchable, though this is less common.