Is cryotherapy effective for fat dissolution (lipolysis)?

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Last updated: March 16, 2025View editorial policy

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From the Research

Cryotherapy is effective for fat dissolution (lipolysis), with the most recent and highest quality study showing a significant reduction in abdominal fat deposits. The study, published in 2023 1, demonstrated a mean decrease in abdominal circumference of 2.10 cm (3.1%) 3 months after the procedure and 4.03 cm (5.8%) 6 months after the procedure, with a mean decrease in fat layer thickness of 1.25 cm (43.81%) 3 months after the procedure and 1.61 cm (41.73%) 6 months after the procedure.

Key Findings

  • Cryolipolysis has been shown to reduce subcutaneous fat at the treatment site by up to 25% after one treatment 2
  • Improvements were seen in 86% of treated subjects, with a patient satisfaction rate of 73% 2
  • The procedure works by cooling fat cells to temperatures that trigger cell death (apoptosis) without damaging surrounding tissues, after which the body naturally eliminates these damaged fat cells over 1-3 months
  • Side effects are generally mild and temporary, including redness, bruising, and numbness

Considerations

  • Cryotherapy should not be considered a weight loss solution but rather a body contouring option for those already at or near their ideal weight with stubborn fat pockets
  • Traditional methods like diet and exercise remain more effective for overall weight management and fat reduction
  • Those considering cryolipolysis should consult with a qualified healthcare provider to determine if they're suitable candidates
  • The most recent study 1 had a larger sample size and more robust methodology, making its findings more reliable and generalizable.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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