What is the effect of the Valsalva maneuver on the murmur of Mitral (mitral valve) Stenosis?

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From the Guidelines

The Valsalva maneuver typically decreases the intensity of the diastolic murmur heard in mitral stenosis. This effect is due to the decreased venous return to the heart during the strain phase of Valsalva, which reduces left atrial filling and subsequently diminishes the pressure gradient across the stenotic mitral valve, as described in the 2008 guidelines for the management of patients with valvular heart disease 1.

Key Points

  • The Valsalva maneuver decreases the intensity of most cardiac murmurs, including mitral stenosis, with a few exceptions such as hypertrophic cardiomyopathy and mitral valve prolapse 1.
  • The decreased venous return during Valsalva reduces left atrial filling, resulting in a softer murmur as less blood flows through the narrowed valve opening.
  • The characteristic low-pitched, rumbling diastolic murmur of mitral stenosis becomes less audible during the Valsalva maneuver.
  • After release of the Valsalva strain, there is a transient increase in venous return, which may briefly intensify the murmur before it returns to baseline.

Clinical Implications

  • Understanding the physiologic response to Valsalva is valuable during cardiac auscultation to help confirm the diagnosis of mitral stenosis and distinguish it from other cardiac pathologies.
  • The response to Valsalva can be used to differentiate mitral stenosis from other cardiac conditions like hypertrophic cardiomyopathy, where the murmur typically increases during strain 1.

From the Research

Effect of Valsalva Maneuver on Mitral Stenosis Murmur

  • The Valsalva maneuver is used to aid in the diagnosis of various heart conditions, including mitral stenosis 2.
  • However, the provided studies do not directly address the effect of the Valsalva maneuver on the murmur of mitral stenosis.
  • One study discusses the use of bedside maneuvers, including the Valsalva maneuver, in evaluating patients with systolic murmurs, but it does not specifically address mitral stenosis, which is typically associated with a diastolic murmur 3.
  • Another study explains the physiological principles behind the Valsalva maneuver and its effects on cardiac parameters, but it does not provide information on its specific effect on mitral stenosis murmur 4.
  • The other studies focus on the mechanisms and clinical implications of the Valsalva maneuver 5, its effect on blood pressure 6, and its use in echocardiography 2, but they do not provide direct evidence on its effect on mitral stenosis murmur.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Valsalva maneuver in echocardiography.

Journal of echocardiography, 2017

Research

Bedside diagnosis of systolic murmurs.

The New England journal of medicine, 1988

Research

On systolic murmurs and cardiovascular physiological maneuvers.

Advances in physiology education, 2012

Research

The Valsalva maneuver: mechanisms and clinical implications.

Heart & lung : the journal of critical care, 1984

Research

Effect of position on valsalva maneuver: supine versus 20 degree position.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2008

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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