What is the recommended treatment for a cat bite?

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Last updated: September 19, 2025View editorial policy

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Cat Bite Treatment

Cat bite wounds require immediate thorough cleaning with soap and water, followed by antibiotic prophylaxis with amoxicillin-clavulanate for 3-5 days to prevent infection, as cat bites have a high infection rate of 20-80%. 1, 2

Initial Management

  1. Wound Cleaning:

    • Immediate and thorough washing of all bite wounds with soap and water
    • Follow with povidone-iodine solution irrigation as a virucidal agent
    • Irrigate for approximately 15 minutes 2
    • Avoid high-pressure irrigation which may spread bacteria into deeper tissues 2
  2. Wound Assessment:

    • Evaluate depth, location, and time elapsed since bite
    • Hand wounds carry the highest risk of infection
    • Check for potential damage to tendons, joints, bones, or nerves
    • Consider radiography to rule out foreign bodies (broken teeth) 2

Antibiotic Treatment

Primary Antibiotic Choice:

  • Amoxicillin-clavulanate 875/125 mg twice daily for 3-5 days 2, 1
  • This covers Pasteurella multocida (found in ~90% of cats) and other common pathogens 1

For Penicillin-Allergic Patients:

  • Doxycycline 100 mg twice daily (not for children under 8 years)
  • Alternative: Fluoroquinolone plus metronidazole 2

Special Considerations

  1. Tetanus Prophylaxis:

    • Evaluate tetanus vaccination status
    • Administer tetanus toxoid if status is outdated (>5 years) or unknown 2
  2. Rabies Assessment:

    • Determine vaccination status of the cat if known
    • A healthy domestic cat that bites may be confined and observed for 10 days
    • For stray/unknown cats, consult local health officials regarding rabies post-exposure prophylaxis
    • If rabies is suspected, administer rabies immune globulin (RIG) and vaccine 2
  3. Wound Closure:

    • Generally, cat bite wounds should not be closed primarily due to high infection risk
    • Facial wounds may be closed if there has been meticulous wound care and antibiotic prophylaxis 2

High-Risk Situations Requiring More Aggressive Management

  • Deep puncture wounds (common with cat bites)
  • Hand or face wounds
  • Wounds near joints or tendons
  • Immunocompromised patients
  • Delayed presentation (>8 hours)
  • Signs of established infection (redness, swelling, pain, purulent discharge)

Follow-up

  • Schedule follow-up within 24-48 hours to assess for signs of infection
  • Monitor for increasing redness, swelling, pain, warmth, or drainage
  • Consider hospitalization and IV antibiotics if infection progresses despite appropriate therapy 2

Common Pitfalls to Avoid

  1. Underestimating cat bites: Despite their small appearance, cat bites have a much higher infection rate (20-80%) than dog bites (3-18%) due to their puncture-type wounds and high carriage of Pasteurella multocida 1, 3

  2. Delayed treatment: Cat bite infections can progress rapidly, particularly those involving the hand

  3. Inadequate antibiotic coverage: Empiric therapy must cover Pasteurella multocida, which is sensitive to penicillins but resistant to dicloxacillin, cephalexin, and clindamycin 1

  4. Insufficient wound cleaning: Thorough irrigation is critical to reduce bacterial load and prevent infection 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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