From the Guidelines
The correction factor calculation for regular (short-acting) insulin is typically 1 unit of insulin for every 50 mg/dL of glucose above the target level.
Correction Factor Calculation
- The correction factor is used to calculate the amount of insulin needed to correct high blood glucose levels.
- The American Diabetes Association recommends using a correction factor of 1 unit of insulin for every 50 mg/dL of glucose above the target level 1.
- This means that if the patient's blood glucose level is 200 mg/dL and the target level is 150 mg/dL, the correction dose would be 1 unit of insulin for every 50 mg/dL above the target level, which is 1 unit for 50 mg/dL (200-150 mg/dL).
Important Considerations
- The correction factor may vary depending on the individual patient's insulin sensitivity and other factors.
- It is essential to monitor the patient's blood glucose levels regularly and adjust the correction factor as needed to avoid hypoglycemia or hyperglycemia.
- The use of correction insulin should be individualized and based on the patient's specific needs and circumstances 1.
Insulin Regimens
- Regular (short-acting) insulin can be used as part of a multidose regimen, which typically includes a combination of basal and bolus insulins 1.
- The choice of insulin regimen should be based on the patient's lifestyle, preferences, and medical history, as well as the availability and cost of different insulin products 1.
From the Research
Correction Factor Calculation for Regular (Short-Acting) Insulin
The correction factor calculation for regular (short-acting) insulin can be determined using various formulas.
- According to the study 2, the correction factor (CorrF) can be calculated as CorrF = 1960/TDD, where TDD is the total daily dose of insulin.
- Another study 3 suggests that the insulin sensitivity factor (ISF) can be estimated using the 1800 rule, which is ISF = 1800/TDD. However, this study found that the 1800 rule was only appropriate for morning correction doses and not for afternoon or evening doses.
- The study 4 provides a formula for estimating the correction factor (CF) as CF = 1500/TDD.
- It is essential to note that these formulas may not be directly applicable to all individuals, and the correction factor may vary depending on factors such as age, body mass index, pubertal stage, diabetes duration, and insulin-to-carbohydrate ratio, as suggested by the study 3.
Key Considerations
- The total daily dose (TDD) of insulin is a critical factor in determining the correction factor.
- The insulin-to-carbohydrate ratio (ICR) and other factors, such as age and body mass index, may also influence the correction factor.
- The correction factor may vary throughout the day, with higher correction dose requirements in the morning, as found in the study 3.
- The use of formulas to derive appropriate pump settings, including the correction factor, is crucial for optimal glucose control, as emphasized by the study 2.