From the Guidelines
The Trilogy inhaler is not a ventilator, but rather a type of ventilatory support device that provides noninvasive ventilation (NIV) therapy. The Trilogy device is designed to provide a range of ventilation modes, including invasive and noninvasive options, to support patients with respiratory failure 1.
Key Features of Trilogy
- Provides noninvasive ventilation (NIV) therapy
- Offers a range of ventilation modes, including invasive and noninvasive options
- Designed to support patients with respiratory failure
Clinical Application
The use of NIV, such as with the Trilogy device, is recommended for various aetiologies of acute respiratory failure (ARF), including exacerbation of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema, and de novo hypoxaemic respiratory failure 1.
Important Considerations
When using the Trilogy device, it is essential to follow the guidelines and recommendations provided by the European Respiratory Society/American Thoracic Society, which are based on the most current literature and the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology 1.
Patient Care
Health professionals should take the guidelines into account in their clinical practice and make appropriate and accurate decisions in consideration of each patient’s health condition, in consultation with that patient and the patient’s caregiver where appropriate and/or necessary 1.
From the Research
Definition and Purpose of Trilogy Inhaler (Ventilator)
- The Trilogy inhaler, also known as a ventilator, is a device used to support patients with respiratory failure by providing mechanical ventilation 2, 3.
- The primary purpose of a ventilator is to ensure sufficient gas exchange in patients with acute respiratory insufficiency, which can be caused by various conditions such as acute respiratory distress syndrome or chronic obstructive pulmonary disease 4, 3.
Modes and Settings of Mechanical Ventilation
- Mechanical ventilation can be delivered in different modes, including invasive and noninvasive ventilation, and the choice of mode depends on the patient's specific needs and condition 2, 3.
- The settings of mechanical ventilation, such as tidal volume, respiratory rate, and positive end-expiratory pressure, are crucial in ensuring effective gas exchange and minimizing the risk of lung injury 4, 3.
Adjunctive Therapies to Mechanical Ventilation
- Adjunctive therapies, such as inhaled nitric oxide and heliox, can be used in conjunction with mechanical ventilation to support patients with acute respiratory failure 5.
- These therapies can help minimize injurious settings and support adequate gas exchange, but their use should be based on a clear understanding of the physiologic basis and evidence 5.
Management of Patients Requiring Prolonged Mechanical Ventilation
- Patients requiring prolonged mechanical ventilation have different needs and resource consumption patterns than patients in acute ICUs, and specialized venues, management strategies, and reimbursement schemes are emerging to address these issues 6.
- The management of patients requiring prolonged mechanical ventilation involves a comprehensive approach, including assessment, management, and reimbursement issues, and recommendations have been developed to address these issues 6.