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Last updated: September 19, 2025View editorial policy

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Differential Diagnosis for Rib Fracture

Single Most Likely Diagnosis

  • Trauma: This is the most common cause of rib fractures, resulting from direct blows to the chest, such as those sustained in motor vehicle accidents, falls, or assaults. The mechanism of injury and clinical presentation (e.g., chest pain, tenderness, and deformity) typically point towards this diagnosis.

Other Likely Diagnoses

  • Osteoporosis: Weakened bones due to osteoporosis can lead to rib fractures with minimal trauma or even spontaneously. This is more common in elderly patients.
  • Cancer: Metastatic disease to the ribs (e.g., from breast, lung, or prostate cancer) can cause pathological fractures.
  • Infection: Osteomyelitis or infections of the soft tissues around the ribs can lead to weakening and potential fracture.

Do Not Miss Diagnoses

  • Pulmonary Embolism: While not directly causing rib fractures, the pain from a pulmonary embolism can be mistaken for musculoskeletal pain, including that from a rib fracture. Missing this diagnosis can be fatal.
  • Aortic Dissection: Chest pain from an aortic dissection can sometimes be confused with the pain from rib fractures. This is a medical emergency.
  • Myocardial Infarction: Chest pain is a common symptom, and while the pattern and nature can differ from rib fracture pain, it's crucial not to miss this potentially fatal condition.

Rare Diagnoses

  • Fibrous Dysplasia: A rare condition where normal bone is replaced with fibrous tissue, leading to weakened bones that can fracture more easily.
  • Osteogenesis Imperfecta: A genetic disorder characterized by fragile bones, which can lead to fractures with minimal trauma.
  • Rib Tumors: Primary or metastatic tumors of the ribs can cause fractures, though this is less common than other causes.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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