What are the causes of persistent vomiting?

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Last updated: March 16, 2025View editorial policy

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Differential Diagnosis for Persistent Vomiting

  • Single Most Likely Diagnosis
    • Gastroenteritis: This is often the most common cause of persistent vomiting, especially in children and young adults, due to viral or bacterial infections.
  • Other Likely Diagnoses
    • Food poisoning: Similar to gastroenteritis, food poisoning from consuming contaminated food can lead to persistent vomiting.
    • Gastritis: Inflammation of the stomach lining can cause persistent vomiting, often due to infection, medication, or excessive alcohol consumption.
    • Intestinal obstruction: A blockage in the intestines can lead to severe vomiting, which is persistent and may be accompanied by abdominal pain and constipation.
    • Pregnancy: Morning sickness is a common symptom of early pregnancy, which can manifest as persistent vomiting.
  • Do Not Miss Diagnoses
    • Appendicitis: Although abdominal pain is the primary symptom, persistent vomiting can occur, especially if the appendix ruptures.
    • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain and persistent vomiting.
    • Kidney stones: Severe pain and persistent vomiting can be symptoms of kidney stones, particularly if they cause an obstruction.
    • Meningitis: In severe cases, meningitis can cause persistent vomiting, especially in children, along with symptoms like headache, fever, and stiff neck.
  • Rare Diagnoses
    • Brain tumors: Increased intracranial pressure from brain tumors can cause persistent vomiting, often accompanied by headache and visual disturbances.
    • Cyclic vomiting syndrome: A rare condition characterized by recurring episodes of severe vomiting, often without an identifiable cause.
    • Addison's disease: A rare endocrine disorder where the adrenal glands do not produce enough cortisol and aldosterone, leading to symptoms like persistent vomiting, weight loss, and fatigue.
    • Porphyria: A group of rare genetic disorders that can cause persistent vomiting, abdominal pain, and neurological symptoms due to the accumulation of porphyrins.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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