When to Start Oral Contraceptive Pills (OCPs)
Oral contraceptive pills can be started at any time during the menstrual cycle if it is reasonably certain that the woman is not pregnant, with specific timing recommendations based on menstrual status and postpartum condition. 1
Starting OCPs Based on Menstrual Cycle Status
During Regular Menstrual Cycles
If started within the first 5 days of menstrual bleeding:
- No additional contraceptive protection needed
- Immediate effectiveness 1
If started >5 days since menstrual bleeding began:
- Use backup contraception (condoms) or abstain from sex for the first 7 days
- Full effectiveness achieved after 7 consecutive days of active pills 1
During Amenorrhea (Not Postpartum)
- Can start at any time if pregnancy is reasonably excluded
- Must use backup contraception or abstain from sex for the first 7 days 1
Postpartum Initiation
For Breastfeeding Women
- If <1 month postpartum: Can start (U.S. MEC 2 - benefits generally outweigh risks)
- If ≥1 month postpartum: Can start (U.S. MEC 1 - no restrictions) 1, 2
- If <6 months postpartum, amenorrheic, and fully/nearly fully breastfeeding:
- No additional contraceptive protection needed
- Note: Progestin-only pills are preferred for breastfeeding women as they don't affect milk production 2
For Non-Breastfeeding Women
- Can start at any time, including immediately postpartum (U.S. MEC 1)
- If ≥21 days postpartum and menstrual cycles haven't returned:
- Use backup contraception for 7 days 1
- If initiating 4 weeks postpartum:
- Consider increased risk of thromboembolism during postpartum period
- Use backup method until taking active pills for 7 consecutive days 3
After Abortion or Miscarriage
- Can start within the first 7 days, including immediately post-abortion
- Backup contraception needed unless started at time of surgical abortion 1
When Switching from Another Contraceptive Method
- Can start immediately if pregnancy is reasonably excluded
- May need backup contraception depending on timing relative to menstrual cycle 1
Starting Methods
Sunday Start Method
- Take first pill on the first Sunday after menstruation begins
- If menstruation begins on Sunday, start that day
- Use backup contraception for first 7 days
- Take one pill daily without interruption 3
Day 1 Start Method
- Take first pill on the first day of menstrual bleeding
- No backup contraception needed if started within first 5 days of cycle
- Take one pill daily without interruption 3
Common Pitfalls and Management
Missed Pills
- 1 missed pill: Take as soon as remembered, then continue regular schedule
- 2 consecutive missed pills (Week 1 or 2): Take 2 pills for 2 days, then resume normal schedule with backup for 7 days
- 2 consecutive missed pills (Week 3) or ≥3 missed pills: Discard pack, start new pack immediately, use backup for 7 days 3
Vomiting or Severe Diarrhea
- Continue taking pills if possible
- Use backup contraception until 7 consecutive days of active pills after resolution
- Consider emergency contraception if vomiting/diarrhea occurred in first week of new pack and unprotected sex occurred 1
Special Considerations
- OCPs have additional benefits beyond contraception, including management of menstrual disorders, endometriosis, acne, and premenstrual symptoms 4, 5
- Combined OCPs have a typical use failure rate of 7-9% 4, 5
- Blood pressure should be measured before initiating hormonal contraceptives 2
The timing of OCP initiation should be tailored to maximize both contraceptive effectiveness and patient convenience, with appropriate guidance on backup methods when needed.