Bone Density Screening in Women with Moderate Osteoporosis
For women with a history of moderate osteoporosis, there is no specific age to stop bone density screening, and monitoring should continue indefinitely as long as the results would impact treatment decisions and the patient would benefit from fracture prevention. 1
Understanding the Need for Continued Monitoring
Osteoporosis is a chronic condition that requires ongoing management even after diagnosis. For patients with established moderate osteoporosis:
- The diagnosis of osteoporosis persists even if subsequent DXA T-scores improve to above -2.5 2
- Patients with osteoporosis remain at elevated risk for fracture even if normal BMD is achieved through treatment 2
- Skeletal deterioration resumes when medication is discontinued—sooner for non-bisphosphonates and later for bisphosphonates 2
Monitoring Intervals for Women with Established Osteoporosis
For women with diagnosed moderate osteoporosis:
- Standard monitoring interval is 2 years 1
- Shorter intervals (1 year) are recommended for:
- Patients initiating new therapy
- Patients at risk for substantial short-term decreases in bone mineralization
- Patients on glucocorticoid therapy 1
- Scan intervals less than 1 year are discouraged 1
Special Considerations for Older Women
While there are no specific guidelines on when to stop screening in women with established osteoporosis:
- There are few data on osteoporosis treatment in women older than 85 years of age 3
- Patients who have already received a diagnosis of osteoporosis require additional testing for diagnostic purposes or to monitor response to treatment, which is different from screening recommendations 3
- The decision to continue monitoring should consider:
- Life expectancy
- Willingness to continue treatment
- Potential for treatment modification based on results
Technical Considerations for Follow-up DXA Scans
To ensure accurate monitoring:
- Follow-up DXA should be performed on the same machine as the baseline scan 1
- Absolute BMD values in g/cm², not T-scores, should be compared on follow-up scans 1
- Significant decreases in BMD should meet or exceed the least significant change (LSC), typically 2.8-5.6% depending on precision error 1
Clinical Decision-Making Based on Monitoring Results
- Patients receiving treatment who demonstrate decreasing BMD on follow-up scans may require adjustment in their pharmacotherapy regimen 1
- Previous fragility fracture, regardless of bone mineral density, is an indication for continued treatment 1, 4
- Treatment should continue for patients with T-score ≤ -2.5 at any major site 1
Pitfalls to Avoid
Don't discontinue monitoring based solely on age: Unlike screening recommendations for the general population, patients with established osteoporosis benefit from continued monitoring regardless of age.
Don't assume treatment success is permanent: Even after achieving improved BMD, the diagnosis of osteoporosis persists, and risk of fracture remains elevated 2.
Don't use T-scores alone for follow-up comparisons: Use absolute BMD values when comparing sequential scans 1.
Don't scan more frequently than recommended: Intervals less than 1 year are discouraged as they may not show clinically meaningful changes 1.