Management of Acute Toothache
For acute toothache management, a combination of ibuprofen and acetaminophen is recommended as first-line pharmacological treatment, with immediate dental referral for definitive treatment of the underlying cause. 1, 2
Initial Assessment and Diagnosis
Determine the likely cause of toothache:
- Dental trauma (fracture, luxation, avulsion)
- Pulpal inflammation/infection
- Periodontal disease
- Pericoronitis (inflammation around partially erupted teeth)
Key clinical findings to assess:
- Pain characteristics (spontaneous, provoked, constant, intermittent)
- Presence of swelling, abscess, or parulis (gingival boil)
- Tooth mobility
- Tooth discoloration
- Sensitivity to percussion or temperature
Pharmacological Management
First-Line Treatment
- Combination therapy: Ibuprofen 400mg plus acetaminophen 1000mg every 6 hours as needed 2
- This combination provides superior pain relief compared to either medication alone
- Maximum daily dose: Ibuprofen 2400mg, acetaminophen 4000mg
Alternative Options
- Ibuprofen 400mg every 4-6 hours (if acetaminophen is contraindicated)
- Acetaminophen 1000mg every 6 hours (if NSAIDs are contraindicated)
- For children: NSAIDs alone or in combination with acetaminophen at age-appropriate doses 1
Important Cautions
- Avoid opioids for dental pain management when possible
- For children, codeine and tramadol are contraindicated per FDA guidelines 1
- Monitor for acetaminophen toxicity if patient has been self-medicating (maximum 4g/day) 3
Non-Pharmacological Management
For Fractured Teeth
- Uncomplicated enamel fractures: Smooth rough edges if present 4
- Enamel and dentin fractures: Cover exposed dentin to reduce sensitivity and prevent bacterial contamination 4
- Complicated fractures (with pulp exposure): Immediate dental referral 4
For Luxated Teeth
- Minor displacement: Gentle repositioning if possible 5
- Severe displacement: Immediate dental referral 5
For Avulsed Permanent Teeth
- Immediate replantation is the treatment of choice 4
- If replantation not possible, store tooth in milk, Hank's Balanced Salt Solution, or saliva (never water) 4
- Immediate dental referral 5
Definitive Management
- All patients with toothache should be referred for definitive dental treatment
- Timing of referral depends on severity:
- Immediate (same day): Severe pain, facial swelling, signs of spreading infection, trauma with pulp exposure
- Urgent (1-2 days): Moderate pain, localized abscess/parulis
- Routine (within 1 week): Mild pain, uncomplicated fractures
Special Considerations
For primary (deciduous) teeth:
For patients with signs of infection:
- Consider antibiotics only if systemic involvement (fever, lymphadenopathy, facial swelling)
- Definitive treatment (pulp therapy, extraction) is essential
Follow-up Care
Monitor for:
- Signs of pulpal necrosis (tooth discoloration, parulis formation)
- Spreading infection (increased swelling, trismus, fever)
- Persistent pain despite medication (may indicate need for urgent intervention)
Advise patients on:
- Soft diet for 10 days after dental procedures 4
- Good oral hygiene practices
- Avoiding extremes of temperature with food/drink if tooth is sensitive
Remember that pharmacological management provides only temporary relief. Definitive dental treatment addressing the underlying cause is essential for resolution of toothache.