From the Research
Meclizine and Breast Health
There is limited research directly addressing the impact of meclizine on breast health. However, some studies provide insight into its use and effects in related contexts:
- Meclizine is used to treat motion sickness and vertigo, with its efficacy and mechanism of action studied in various trials 1, 2.
- A study on meclizine metabolism and pharmacokinetics found that it is primarily metabolized by the CYP2D6 enzyme, with genetic polymorphism contributing to interindividual variability 2.
- Meclizine has been used to treat withdrawal symptoms after discontinuation of transdermal scopolamine therapy, with successful results in a case report 3.
- Meclizine has been shown to reduce nausea and vomiting associated with emergency contraceptive pills, although it may cause drowsiness 4.
- A review of questions to a web-based medicines information service for pregnant and breastfeeding women found that meclizine was one of the top five medications asked about, with many questions concerning its safety during pregnancy and breastfeeding 5.
Safety During Pregnancy and Breastfeeding
While there is no direct evidence on meclizine's effects on breast health, its safety during pregnancy and breastfeeding has been a concern for many women:
- The majority of questions about meclizine to the SafeMotherMedicine service concerned its use during pregnancy (49%) or breastfeeding (72%) 5.
- Most questions about meclizine were answered with information indicating no or low risk for the fetus or breastfed infant 5.
- However, the available evidence does not specifically address the impact of meclizine on breast health, such as breast cancer risk or breast milk production.