What is the recommended treatment for a tonsillar abscess?

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Treatment of Tonsillar Abscess

The recommended treatment for a tonsillar abscess includes drainage of the abscess (via needle aspiration, incision and drainage, or immediate tonsillectomy) combined with appropriate antibiotic therapy targeting both Group A streptococcus and oral anaerobes. 1

Diagnosis

  • Clinical presentation typically includes:

    • Fever
    • Severe sore throat
    • Dysphagia (difficulty swallowing)
    • Trismus (limited mouth opening)
    • "Hot potato" voice
    • Unilateral tonsillar swelling with deviation of the uvula
    • Tender cervical lymphadenopathy
  • Diagnostic confirmation may include:

    • Ultrasonography
    • CT scanning (in complex cases)

Treatment Algorithm

1. Drainage Procedure

One of the following drainage procedures must be performed:

  • Needle aspiration: Gold standard for initial management 2

    • Advantages: Can be performed in outpatient setting, less invasive
    • Success rate: Approximately 87% 3
  • Incision and drainage: Alternative approach

    • Advantages: May provide more complete drainage
    • Success rate: Approximately 90% 3
  • Immediate tonsillectomy: Reserved for advanced cases or recurrent abscesses 2

    • Consider for patients with history of >1 peritonsillar abscess 4

2. Antibiotic Therapy

Peritonsillar abscesses are polymicrobial infections, requiring antibiotics effective against both Group A streptococcus and oral anaerobes 1.

First-line options:

  • Penicillin (IV or oral after initial improvement)
    • Remains an excellent choice for therapy after drainage 5
    • 97% of patients respond to penicillin 3

Alternative options (for penicillin allergy or treatment failure):

  • Clindamycin: 300-450 mg orally three times daily for 10 days 6
  • Cephalosporins (cefdinir, cefuroxime, cefpodoxime) 6
  • Amoxicillin-clavulanate (for treatment failures) 6

3. Supportive Care

  • Pain management:

    • NSAIDs or acetaminophen for pain control
    • Warm salt water gargles
    • Adequate hydration
  • Corticosteroids:

    • May help reduce symptoms and speed recovery 1

Special Considerations

Outpatient vs. Inpatient Management

Most patients can be managed as outpatients 1, but hospitalization is indicated for:

  • Inability to maintain oral hydration
  • Respiratory distress or airway concerns
  • Significant comorbidities
  • Treatment failure
  • Extension of infection into deep neck tissues

Complications to Monitor

  • Airway obstruction
  • Aspiration
  • Extension of infection into deep neck spaces
  • Dehydration

Follow-up

  • Follow-up within 24-48 hours to assess response to therapy
  • Consider tonsillectomy after resolution for patients with recurrent peritonsillar abscesses (history of >1 episode) 4

Microbiology Considerations

Common pathogens include:

  • Streptococcus pyogenes (most common) 7
  • Staphylococcus aureus 7
  • Anaerobic bacteria
  • Other organisms: Haemophilus influenzae, Pseudomonas aeruginosa, Escherichia coli 7

Local resistance patterns should be considered when selecting antibiotics, as Staphylococcus aureus may be resistant to penicillin while Streptococcus pyogenes typically remains sensitive 7.

References

Research

Peritonsillar Abscess.

American family physician, 2017

Research

Peritonsillar abscess: diagnosis and treatment.

American family physician, 2002

Research

Management of peritonsillar abscess.

The Journal of laryngology and otology, 1991

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Selection of antibiotics after incision and drainage of peritonsillar abscesses.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1999

Guideline

Treatment of Group A Streptococcal Pharyngitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Bacteriology and antibiotic susceptibility pattern of peritonsillar abscess.

JNMA; journal of the Nepal Medical Association, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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